Phytochemical Screening and Free Radical Scavenging Activity of Cinnamomum tamala Leaf Extract

Abstract

Traditional plant-based medicines are still needed by the whole world for their primary healthcare benefits. The phytochemicals or plant extract could be used to treat different diseases and new formulation for the drug discovery in pharmaceuticals. Cinnamomum tamala is commonly called as Indian bay leaf or Tejpatta. The leaves and bark of Cinnamomum tamala are used to cure various diseases due to its various properties including astringent, stimulant and carminative. Hence, the objective of this study was to determine the comparative phytochemical screening and free radical scavenging activity of the leaf of Cinnamomum tamala. To achieve this, extract was prepared in three solvents (ethanol, ethanol, aqueous and chloroform). Phytochemical screening (qualitative and quantitative) was evaluated in all the three fractions to compare the solubility of various bioactive components. Phytochemical screening showed the presence of polyphenols, flavonoids, alkaloids, flavones and flavonols, tannins, carbohydrates, amino acids and proteins, saponins and glycosides in leaves of Cinnamomum tamala. Quantitative analysis showed that the total polyphenolic content, total flavonoids content, total alkaloids and total flavones and flavonols content in the hydroalcoholic extract was 48.1 mg GA (gallic acid)/g, 22.1 mg QE (Quercetin)/g, 59.9 mg/g and 1.75 mg RE (Rutin)/g, respectively. DPPH free radical assay revealed that Cinnamomum tamala hydroalcoholic leaf extract at a 100 µm/ml concentration showed 96.99± 0.99% inhibition activity. It can be concluded that most of the bioactive components are found soluble in hydroalcoholic solvent. Cinnamomum tamala hydroalcoholic leaf extract contains various bioactive and also exhibits significant free radical scavenging activity. Hence, it can be used as an alternative remedy for the treatment of various diseases.

Cinnamomum impressinervium meisn.: antioxidant and antimicrobial activities

“…Wells were bored, and then 2 mL of an extract made from Cinnamon impressinervium leaves was added to the medium. An hour was spent on inoculation to guarantee the strong diffusion of antimicrobial agents to the medium [10,18,19].…”

Qualitative And Quantitative Analysis of Cinnamomum Tamala Leaf Extract

“…Among the Cinnamomum species, the Cinnamomum tamala leaves exhibit various medicinal properties and used as a food flavor and spice (22). The leaves of Cinnamomum tamala shows various phytochemical properties with abundant presence of flavonoids, phenols, tannins, steroids and saponins (23). Phytochemical analysis of the leaf extract of Cinnamomum tamala revealed the presence of various bioactive compound which possess medicinal properties.…”

Comparative antibacterial and antifungal activities of Cinnamomum Tamala Nees & Eberm. and Taraxicum officinale leaf extract

“…6 Plants have been used as complementary sources of medicines from centuries against various ailments due to their antioxidant, hypoglycaemic, hypolipidemic, hepatoprotective, neuroprotective, and nephroprotective activities, various therapeutics are prepared from medicinal plants for the treatment of diabetes and related complications. [7][8][9][10][11][12][13][14][15] Marvellous research has been conducted on pharmacotherapy, because traditional options of treatment could be better substitute of allopathic drugs, due various reasons such as ease of availability, costeffective and devoid side defects, 16,17 Pilot study revealed that Cinnamomum tamala and Taraxicum officinale leaves contains various bioactive components, these bioactive components might be helpful to combat worsen reproductive disorder. Considering the medicinal profile of these two leaf extract.…”