Phytochemical Screening, Antimicrobial, and Antioxidant Activities of Root and Leaf Extracts of Leucas Aspera

Vasudha, K; Archana, D.; Mutyalamma, B; Kishori, B.

doi:10.22159/ajpcr.2019.v12i3.29085

Cited by 3 publications

(1 citation statement)

References 21 publications

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“…D*-extract also possessed concentrated biological important phytochemicals such as polyphenols and flavonoids. Kumar, Nehra [60] showed that E. faecalis is most sensitive to plant compounds such as polyphenols. Therefore, this specific strain (as compared to other strains) in our study showed increased sensitivity to H-extract, D-extract, and D*-extract.…”

Section: Plos Onementioning

confidence: 99%

Solvent based fractional biosynthesis, phytochemical analysis, and biological activity of silver nanoparticles obtained from the extract of Salvia moorcroftiana

Khan,

Wahab

et al. 2023

PLoS ONE

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Multi-drug resistant bacteria sometimes known as “superbugs” developed through overuse and misuse of antibiotics are determined to be sensitive to small concentrations of silver nanoparticles. Various methods and sources are under investigation for the safe and efficient synthesis of silver nanoparticles having effective antibacterial activity even at low concentrations. We used a medicinal plant named Salvia moorcroftiana to extract phytochemicals with antibacterial, antioxidant, and reducing properties. Three types of solvents; from polar to nonpolar, i.e., water, dimethyl sulfoxide (DMSO), and hexane, were used to extract the plant as a whole and as well as in fractions. The biosynthesized silver nanoparticles in all extracts (except hexane-based extract) were spherical, smaller than 20 nm, polydispersed (PDI ranging between 0.2 and 0.5), and stable with repulsive force of action (average zeta value = -18.55±1.17). The tested bacterial strains i.e., Klebsiella pneumoniae, Pseudomonas aeruginosa, Staphylococcus aureus, and Enterococcus faecalis were found to be sensitive to even small concentrations of Ag-NPs, especially P. aeruginosa. The antibacterial effect of these Ag-NPs was associated with their ability to generate reactive oxygen species. DMSO (in fraction) could efficiently extract antibacterial phytochemicals and showed activity against MDR bacteria (inhibition zone = 11–12 mm). Thus, the antibacterial activity of fractionated DMSO extract was comparable to that of Ag-NPs because it contained phytochemicals having solid antibacterial potential. Furthermore, Ag-NPs synthesized from this extract owned superior antibacterial activity. However, whole aqueous extract-based Ag-NPs MIC was least (7–32 μg/mL) as compared to others.

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Section: Plos Onementioning

confidence: 99%

Solvent based fractional biosynthesis, phytochemical analysis, and biological activity of silver nanoparticles obtained from the extract of Salvia moorcroftiana

Khan,

Wahab

et al. 2023

PLoS ONE

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Novel Synthesis and Biophysical Characterization of Zinc Oxide Nanoparticles Using Virgin Coconut Oil

Lakshmi,

Vamsi Krishna,

Rao

et al. 2024

ACS Omega

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One of the primary concerns in the field of green synthesis of nanoparticles (NPs) utilizing plant materials is the scarcity of high purity, challenges in achieving large-scale production, and limited global accessibility. Hygienic preparation and safe storage of plant extracts are also considerable challenges in this field. So, an investigation was started to overcome these limitations. Virgin coconut oil (VCO) in its purest form is available commercially all over the world. Also, it has high medicinal value with excellent biomedical applications. Very limited work has been reported on oils as bio reducers and stabilizers. In those reports, they used a few chemicals as mediators in the processes of synthesis and cleaning. So, to the best of our knowledge, for the first time, zinc oxide (ZnO) NPs were synthesized using VCO as a reducing and capping agent with zero chemical mediators. A comprehensive investigation of the structural, microstructural, and optical properties was reported. X-ray diffraction confirms the formation of VCO-ZnO NPs with an average crystallite size of 32.81 nm in a hexagonal structure. UV characteristics confirm quantum confinement through a well-defined SPR near 223 nm with fwhm of 67 nm and a direct band gap at 3.96 eV. FTIR reveals the capping of VCO through carboxylic functional groups, particularly the −COO– group of coconut oil at 1770 cm –1 with a shift of about 30 cm –1 compared to plain VCO. TEM confirms the polycrystalline nature with nearly spherical and 10–22 nm particle size. The zeta potential of −15.4 ± 5.0 mV signifies the stability and antiagglomeration properties. FESEM with EDS results confirms morphological excellence, the purity level of synthesized NPs (99.5%), and the prominent scalability of NPs (84.38% yield). Finally, as-synthesized VCO-ZnO NPs showed very good antioxidant (IC 50 78.991, 51.464, and 4.677 μg/mL in DPPH, ABTS, and FRAP assays, respectively), anti-inflammatory (IC 50 22.42 μg/mL in protein denaturation), antimicrobial (MIC 0.156 mg/mL for Pseudomonas and 0.316 mg/mL for S. aureus ), and antidiabetic properties (IC 50 88.45 and 147.67 μg/mL for α-amylase and α-glucosidase assays, respectively).

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Nutritional and chemical composition of black velvet tamarind (Dialium guineense Willd) and its influence on animal production: A review

et al. 2023

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The world population is expected to double by 2050, creating a greater demand for animal protein sources. This calls for an increase in the supply of animal-derived foods in order to avoid food scarcity in the future. Non-ruminants, which would have been a panacea to this increased demand for animal-derived foods, have suffered from the rising costs of feed ingredient world-wide. The increase in the prices of conventional feedstuffs have attracted the attention of researchers on the potentials of lesser-known tropical medicinal plants like Dialium guineense Willd (black velvet tamarind) as a feed resource for non-ruminants. The increase in prices of conventional feedstuffs have attracted the attention of researchers on the potentials of lesser-known tropical medicinal plants. One such lesser-known tropical plant that can be used in chicken and livestock production is black velvet tamarind. The plant is found in many parts of the world. It belongs to the family Fabaceae, has high forage yield, resistant to drought and insects, and does not require annual cultivation. The whole seed is moderate in crude protein and fibre but high in carbohydrates. The leaf, on the other hand, is low in carbohydrate, moderate in crude protein, and high in ash. D. guineense stem bark and fruit are excellent source of essential oils, and rich source of dietary fibre, minerals, and vitamins for monogastrics. The plant is endowed with beneficial phytochemicals such as alkaloids, tannins, phenols, flavonoids which may serve as natural alternatives to in-feed antibiotics. D. guineense has beneficial pharmacological effects including antioxidant and antimicrobial properties. The purpose of this study was to review the body of knowledge on the nutritional and chemical composition of D. guineense and its impact in animal production.

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Phytochemical Screening, Antimicrobial, and Antioxidant Activities of Root and Leaf Extracts of Leucas Aspera

Cited by 3 publications

References 21 publications

Solvent based fractional biosynthesis, phytochemical analysis, and biological activity of silver nanoparticles obtained from the extract of Salvia moorcroftiana

Solvent based fractional biosynthesis, phytochemical analysis, and biological activity of silver nanoparticles obtained from the extract of Salvia moorcroftiana

Novel Synthesis and Biophysical Characterization of Zinc Oxide Nanoparticles Using Virgin Coconut Oil

Nutritional and chemical composition of black velvet tamarind (Dialium guineense Willd) and its influence on animal production: A review

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