Phytochemical Screening of Ant Plant Myrmecodia rumphii Becc.

Pasaribu, Yenni Pintauli; Buyang, Yorinda; Rettob, Abraham Laurens; Latuheru, Reinyelda D.; Marlissa, Inggrid

doi:10.2991/icst-18.2018.60

Cited by 3 publications

(4 citation statements)

References 7 publications

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“…According to Pasaribu et al (2018), ant nest plants from the genera Hydnophytum and Myrmecodia contain various compounds, making them biologically active. Hydnophytum formicarum Folium contains terpenoids, alkaloids, tannins, glycosides, and saponins, while H. formicarum Cortex contains flavonoids, alkaloids, terpenoids, and glycosides.…”

Section: Phytochemical Screeningmentioning

confidence: 99%

“…Phytochemical screening of ant nest plants M. Beccarii, Myrmecodia sp., and Hydnophytum sp. indicates that all three species contain flavonoids, triterpenoids/steroids, and saponins (Mardany et al 2016;Pasaribu et al 2018). Pasaribu et al (2018) found that the ant nest plant Myrmecodia rumphii Becc.…”

Section: Phytochemical Screeningmentioning

confidence: 99%

“…indicates that all three species contain flavonoids, triterpenoids/steroids, and saponins (Mardany et al 2016;Pasaribu et al 2018). Pasaribu et al (2018) found that the ant nest plant Myrmecodia rumphii Becc. contains various secondary metabolites, including triterpenoids/ steroids, phenolics, flavonoids, alkaloids, and tannins, distributed in methanol, ethyl acetate, and nhexane solvents.…”

Section: Phytochemical Screeningmentioning

confidence: 99%

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Identification, screening, and analysis of secondary metabolite content in methanol extracts of ant nests plant tubers from Aceh, Indonesia

ROSLIZAWATY,

GHOLIB,

RAHMI

et al. 2024

Biodiversitas

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Abstract. Roslizawaty R, Gholib G, Rahmi N, Khairan K, Idroes R, Syafruddin S, Abrar M. 2023. Identification, screening, and analysis of secondary metabolite content in methanol extracts of ant nests plant tubers from Aceh, Indonesia. Biodiversitas 24: 6934-6941. This study aims to identify the chemical components obtained from extracting and partitioning methanol extracts from ant nest tubers (Myrmecodia sp.) originating from Aceh Jaya and Aceh Besar. These extracts were identified using phytochemical screening, Fourier Transform Infrared (FT-IR), and Gas Chromatography-Mass Spectroscopy (GC-MS) methods. The identification results showed that the ant nest plant from Aceh Jaya belongs to the species Myrmecodia tuberosa Jack. The ant nest plant from Aceh Besar belongs to the species Hydnophytum formicarum Jack. Phytochemical screening results showed that the methanol extract from Aceh Jaya's ant nest tubers contained flavonoids, tannins, saponins, and terpenoids, while Aceh Besar's ant nest tubers contained flavonoids, tannins, terpenoids. GC-MS analysis revealed that the major compound found in the methanol extract from Aceh Jaya's ant nest tubers was 2H-oxecin-2-one,3,4,7,8,9,10-hexahydro-4-hydroxy-10-methyl-,[4S-(4R*,5E,10S*)]- constituting 50.63% of the extract. In comparison, the primary compound in the methanol extract from Aceh Besar was resorcinol at 17.92%. FT-IR analysis indicated that the FT-IR spectra of the methanol extracts from Aceh Jaya's ant nest tubers contained O-H, C-H, C=O, C=C alkene, and C=C aromatic groups. At the same time, methanol extracts from Aceh Besar's ant nest tubers also contained O-H, C-H, C=O, C=C alkene, and C=C aromatic groups.

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Section: Phytochemical Screeningmentioning

confidence: 99%

Section: Phytochemical Screeningmentioning

confidence: 99%

Section: Phytochemical Screeningmentioning

confidence: 99%

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Identification, screening, and analysis of secondary metabolite content in methanol extracts of ant nests plant tubers from Aceh, Indonesia

ROSLIZAWATY,

GHOLIB,

RAHMI

et al. 2024

Biodiversitas

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“…Based on an ethnopharmacology study from some selected regions in Indonesia, the genus of Myrmecodia has been used as traditional medicine by the community in East Indonesia, especially in Papua, to treat inflammation, muscle pain relief, and strengthen the body's immunity [9]. Rural people in the Papua community use the tuber (hypocotyl) powder of the Myrmecodia plant as a brewed drink like tea with decoction method [10], [11]. In the Papua region, Myrmecodia pendens Merr.…”

Section: Traditional Usesmentioning

confidence: 99%

Medicinal Properties of Ant Nest Plant (Myrmecodia Genus): A Comprehensive Review

Dirgantara

Insanu

Fidrianny

2022

Open Access Maced J Med Sci

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BACKGROUND: The Myrmecodia genus belongs to the Rubiaceae family, which has the characteristic of an epiphytic plant. This genus spread from Malaysia, through the Philippines, Sumatra, Borneo, Java, New Guinea (Papua), Cape York to the Solomon Islands and Pacific region. It has been empirically proven to treat gout, inflammation, muscle pain relief, strengthen the body’s immunity, and cancer treatment. AIM: This article reviewed the scientific work about the Myrmecodia genus concerning their traditional uses, phytochemical compounds, and pharmacological activities of Myrmecodia. METHODS: The sources were from the scientific literature online database, including Science Direct, PubMed, and Google Scholar between 1978 and 2021. Furthermore, 112 articles were collected, while 61 full-text were assessed for eligibility. RESULTS: The Myrmecodia extract has many pharmacological activities, namely antioxidant, antibacterial, cytotoxic, and anticancer. CONCLUSION: Moreover, this review may be used as scientific literature for the next investigations on the genus Myrmecodia, especially regarding pharmacological properties such as in vitro and in vivo studies and isolation of the active compounds.

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Antibacterial and Antioxidant Superoxide Anion Radical Inhibitors from Myrmecodia pendans: An In silico Study

Kurnia

Ramadhanty

Situmeang

et al. 2023

NPJ

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Background: Ant-nest (Myrmecodia pendans) is an epiphytic plant that can prevent several diseases, including bacterial infections. Diarrhea is caused by Escherichia coli bacteria, while infections in the oral cavity can be caused by Enterococcus faecalis bacteria. Antibacterial activity is also influenced by conditions of Reactive Oxygen Species (ROS). Antioxidants are needed to inhibit the formation of excess ROS in the body. Superoxide anion radicals are included in the generation of ROS, which are produced by several enzymes, such as nicotinamide-adenine dinucleotide phosphate (NADPH) oxidase or commonly known as Nox and xanthine oxidase (XO). Background: Ant-nest (Myrmecodia pendans) is an epiphytic plant that can prevent several diseases, including bacterial infections. Diarrhea is caused by Escherichia coli bacteria, while infections in the oral cavity can be caused by Enterococcus faecalis bacteria. Antibacterial activity is also influenced by conditions of Reactive Oxygen Species (ROS). Antioxidants are needed to inhibit the formation of excess ROS in the body. Superoxide anion radicals are included in the generation of ROS, which are produced by several enzymes, such as nicotinamide-adenine dinucleotide phosphate (NADPH) oxidase or commonly known as Nox and xanthine oxidase (XO). Objective: This study aimed to determine the potential of M. pendans as an antibacterial in vitro and in silico correlation in the formation of superoxide anion radicals. objective: To determine the potential of M. pendans as an antibacterial in vitro and in silico correlation in the formation of superoxide anion radicals. Methods and Materials: The compounds were obtained by column chromatography method, followed by a spectroscopic examination. In vitro test using the disc diffusion method and in silico test using AutoDock 4.2 program were conducted with positive control fosfomycin and allopurinol, tethered to MurA, Nox, and XO enzymes, and visualized using the Discovery Studio 2020. Results: Compound 1 (oleanolic acid ) and compound 2 (pomolic acid) demonstrated antibacterial activity against E.coli but no activity against E. faecalis. Compound 3 (acid-3-hydroxy-eupan-20,24-dien-26-oic) demonstrated no activity against these two bacteria. Based on the in silico results, compound 3 had the best binding energy affinity for all MurA, Nox, and XO enzymes of -6.89, -9.35, and -9.75 Kcal/mol, respectively. Similarly, compounds 1 and 2 had good binding energies for Nox protein of -9.29 Kcal/mol and -6.54 Kcal/mol and XO of -7.66 and -4.7 Kcal/mol, respectively. Conclusion: In vitro results against E.coli and E. faecalis bacteria showed inhibition by compounds 1 and 2 but not by compound 3. Meanwhile, in in silico analysis, all the compounds showed potential as an inhibitor of superoxide anion radicals generated by enzymes Nox and XO. conclusion: In vitro results against E.coli and E. faecalis bacteria showed inhibition by compounds 1 and 2, but not by compound 3. Meanwhile, based on the results of in silico data, compounds 1-3 had the potential to inhibit superoxide radicals. anions to the enzymes Nox and XO. other: -

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Phytochemical Screening of Ant Plant Myrmecodia rumphii Becc.

Cited by 3 publications

References 7 publications

Identification, screening, and analysis of secondary metabolite content in methanol extracts of ant nests plant tubers from Aceh, Indonesia

Identification, screening, and analysis of secondary metabolite content in methanol extracts of ant nests plant tubers from Aceh, Indonesia

Medicinal Properties of Ant Nest Plant (Myrmecodia Genus): A Comprehensive Review

Antibacterial and Antioxidant Superoxide Anion Radical Inhibitors from Myrmecodia pendans: An In silico Study

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