Phytochemical Screening, Total Phenolics Content and Antioxydants Potential of Different parts of Grangea maderaspatana from Burkina Faso

Abstract

This work is a contribution to a better use of Grangea maderaspatana belonging to family Asteracea as a medicinal plant for its phytochemicals. Extracts of different parts of Grangea maderaspatana were thus screened for their phytochemicals, including phenolics, tannins and flavonoids contents and total antioxidant contents.
 The extracts were obtained from the roots, flowers, leafy branches and the whole plant using hexane, dichloromethane, ethyl acetate and methanol. The phytochemical screening was carried out by means of thin layer chromatography, colorimetric and precipitation reactions. Total phenolics contents, total flavonids et totat antioxidants contents were evaluated by spectrophotometric methods.
 The phytochemical screening revealed that G. maderaspatana different parts contained phenolics, tannins, flavonoids, alkaloids, sterols and terpenes at different content. Total phenolics contents ranged from 0.051 to 93.455 mg GAE/g of extract in dichloromethane extract of leafy branches and in the ethyl acetate extract of flowers, respectively. Those of total flavonoids ranged from 82.984 in the roots methanolic extract to 753.337 mg QE/g in the ethyl acetate extract of flowers. Total antioxidant contents, assessed by , and methods are highest in ethyl acetate extracts compared to others extraction solvents.
 maderaspatana contains a variety of secondary metabolites whose levels vary according to the plant part used.

Phytochemical characterization and evaluation of antiplasmodial activity of extracts of Acanthospermum hispidum harvested in Burkina Faso

“…According to the work of Kouassi and al., the methanolic extracts of the leaves and flowers of C. giganteus contained the best levels of total phenolic compounds (118.14 mg GAE/g of extract) [26] . The phenolic compound contents of the methanolic and ethyl acetate extracts of Acanthospermum hispidum remain higher than those reported by Yougoubo Abdoulaye et al in this work on the leafy branches of G. maderaspatana where the contents were 57.921 and 12.260 mg GAE/g of extract respectively for the ethyl acetate and methanol extracts [27] .…”

“…These results are in agreement with the work of Remy K Bationo and al., [25] . In addition, the work of Yougoubo Abdoulaye and al., carried out on the extracts of the leafy branches of G. maderaspatana showed that the ethyl acetate extract contained the best content of total phenolic compounds (57.921 mg GAE/g of extract) followed by the methanol extract (12.260 mg GAE/g extract) and the antioxidant levels were in the same order with 13.209 and 11.355 mg TE/g extract respectively [27] .…”

“…These values are higher than those of our work [25] . In addition, Yougoubo et al, showed that the ethyl acetate fractions were the richest in flavonoids followed by the dichloromethane fractions on all the different parts of G. maderaspatana [27] .…”