Phytochemicals, antioxidant, and anthelmintic activity of selected traditional wild edible plants of lower Assam

Abstract

Objective:Clerodendrum viscosum, Eryngium foetidum, Lippia javanica, and Murraya koenigii are one among the common wild edible plants in Northeast India which are also used as antidiabetic, stomach-ache relieving drugs, etc., The present study was aimed to reveal the phytochemical, antioxidant, and anthelmintic activity of the plants.Materials and Methods:The antioxidant capacity of methanolic extract of plants was studied by 1,1-diphenyl-2-picrylhydrazyl (DPPH), ferric reducing antioxidant power, TBARS, and total antioxidant activity (TAA). Total phenolics, flavonoids, Vitamin C, carbohydrate, and protein are also estimated following standard protocols. Anthelmintic activity of the extracts has also been studied in vitro against trematode parasites.Results:The result showed that the methanolic extracts of plants possess a substantial quantity of alkaloids, phenolics, flavonoids, proteins, carbohydrates, and Vitamin C. Phenolics, flavonoids, and Vitamin C contents were found higher in C. viscosum followed by M. koenigii, L. javanica, and E. foetidum. The in vitro antioxidant assays revealed substantial free radical scavenging property in all the plants. TAA increased in the order C. viscosum > M. koenigii > L. javanica > E. foetidum. Similarly, C. viscosum displayed a better antioxidant capacity with IC50 values 29.74 ± 3.63 μg and 148.77 ± 18.38 μg for DPPH and thiobarbituric acid reactive species, respectively. In addition, the plant extracts also showed good anthelmintic activity against Paramphistomum sp. Time taken for paralysis and death were 0:56 ± 0:09 h and 1:35 ± 0:07 h for L. javanica at 50 mg/mL concentration.Conclusion:The study therefore suggests the importance of tested plants as a natural source of free radical scavenger and plausible veterinary uses.

Phytochemical Constituents and Antioxidant Potential of Crude Extracts from Lippia Javanica (Burm.f.) Spreng Leaves

“…16 Medicinal properties of plants depend on their phytochemical constituents such as steroids, saponin, alkaloids, terpenoids, phenol, proanthocyanidins and tannin. 6 In this study, Lippia Javanica was confirmed to consist of tannin, flavonoids, terpenoids, alkaloids and phenols. This finding corroborated with previous reports on phytochemical screening of Lippia Javanica.…”

“…18 Flavonoid tremendous activities include; anti-viral, anti-inflammatory, anti-bacterial, and anti-oxidant. 6 Alkaloids, Terpenes and Tannin have also been reported to possessed anticancer, antioxidant, anti-pyretic, with different alphabets (a, b, c, d) were significant (p < 0.05). anti-inflammatory, antidiabetic, anti-platelet aggregation and sedative activities.…”

“…Reactive oxygen species (ROS) produced during body's metabolism are implicated in many debilitating diseases including; diabetics, cancer, dementia, multiple sclerosis, cystic fibrosis stroke and heart attack. 6 Antioxidant molecules possessed the capacity to neutralize the effects of those free radicals. Most antioxidants interrupt free radical chain reaction due to their redox properties, thus terminate ROS activities.…”

“…The biological activities of plants are linked to their phytochemical constituents such as phenols, flavonoids, terpenoids, alkaloids, saponins and terpenes. 6 The antioxidant potentials of various plants species have also been reported in the literatures. 2,7…”

Phytochemical, Antioxidant, and Trace Element Analysis of Anthelmintic Plants of North-East India

“…Flavonoids are important secondary metabolite that possesses tremendous medicinal property such as antioxidant, antiinflammatory, anticancer, antibacterial, anti-viral activity etc [29]. The phytochemicals screening of methanolic extracts of A. calamus (MeAc), H. rosa-sinensis (MeHr), C. dactylon (MeCd) and E. floribundus (MeEf) showed high content of carbohydrates and proteins (table 1).…”