Phytochemicals: nutraceuticals and human health

Dillard, Cora J.; German, J. Bruce

doi:10.1002/1097-0010(20000915)80:12<1744::aid-jsfa725>3.3.co;2-n

Cited by 411 publications

(482 citation statements)

References 68 publications

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“…The leaves, fruit, flowers and immature pods of this tree are used as a highly nutritive vegetable in many countries, particularly in India, Pakistan, Philippines, Hawaii and many parts of Africa (D'souza and Kulkarni, 1993;Anwar and Bhanger, 2003;Anwar et al, 2005). Moringa leaves have been reported to be a rich source of β-carotene, protein, vitamin C, calcium and potassium and act as a good source of natural antioxidants; and thus enhance the shelf-life of fat containing foods due to the presence of various types of antioxidant compounds such as ascorbic acid, flavonoids, phenolics and carotenoids (Dillard and German, 2000;Siddhuraju and Becker, 2003). In the Philippines, it is known as 'mother's best friend' because of its utilization to increase woman's milk production and is sometimes prescribed for anemia (Estrella et al, 2000;Siddhuraju and Becker, 2003).…”

Section: Introductionmentioning

confidence: 99%

Moringa oleifera: a food plant with multiple medicinal uses

Anwar

Latif

Ashraf

et al. 2006

Phytotherapy Research

1,528

1,048

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Section: Introductionmentioning

confidence: 99%

Moringa oleifera: a food plant with multiple medicinal uses

Anwar

Latif

Ashraf

et al. 2006

Phytotherapy Research

1,528

1,048

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“…This beneficial effect is mainly associated with the antioxidant activity of phenolic compounds, acting as reducing agents by donating hydrogen, quenching singlet oxygen, acting as chelators and trapping free radicals. These highly reactive molecules are present in biological systems and may oxidise nucleic acids, proteins and lipids, promoting degenerative diseases such as cancer, heart disease, dermal disorders and ageing [1][2][3][4]. Fruit is one of the most important sources of antioxidants such as vitamins (especially vitamin C and vitamin E) and bioactive phytochemicals (polyphenols and carotenoids) [5].…”

Section: Introductionmentioning

confidence: 99%

Phenolic profile and antioxidant activity in apple juice and pomace: effects of different storage conditions

Maragò¹,

Iacopini²,

Camangi³

et al. 2015

Fruits

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-Introduction. Apples have been part of the human diet since ancient times and are one of the most commonly consumed fruit worldwide, rich in phenolic compounds. Phenolics are naturally occurring non-nutritive plant compounds, possessing several health benefits. The effect of storage conditions on phenolics concentrations and on the antioxidant activity of apple juice and pomace was studied. Materials and Methods. Experiments were carried out with two apple varieties, an ancient Tuscan variety, Panaia-red, and a commercial variety, Golden Delicious. The antioxidant activity was assessed by means of two different in vitro tests: scavenging of DPPH• radical, and inhibition of tyrosine nitration mediated by peroxynitrite (ONOO − ). Analyses of juices were carried out immediately after production and after 2 weeks storage in 3 different temperature conditions: 4 • C, -20 • C and room temperature after pasteurisation. Results and discussion. Highly significant differences were recorded between the two varieties, the Panaia-red juice having a higher concentration of phenolic compounds and a higher antioxidant activity. During apple juice storage, phenolic compound concentrations and antioxidant capacity remained quite stable. A correlation between antioxidant activity and phenolic concentration was observed (0.69 r 0.97). Conclusion. The effects of a short storage time and different conditions of storage on the phenolic concentration and antioxidant activity seem to be less relevant than variety effects. The apple pomace revealed an amount of phenolic compounds, ranging from 6.8 to 15.5 mg GAE 100 g −1 DM of total polyphenols, which paves the way for their use as ingredients in foods lacking in polyphenols.Keywords: Italy / apple / Malus domestica / DPPH• radical / phenolics / shelf-life / tyrosine nitration Résumé -Profil phénolique et activité anti-oxydante du jus et du marc de pomme : effets des conditions de stockage. Introduction. Depuis la plus haute Antiquité, les pommes ont fait partie de l'alimentation humaine et constituent l'un des fruits les plus consommés au monde, et riches en composés phénoliques. Les composés phénoliques sont des composés végétaux naturels non nutritifs mais possédant de nombreuses propriétés nutritionnelles bénéfiques pour la santé. L'étude porte sur l'effet des conditions de stockage sur la concentration de ces composés phénoliques et sur l'activité anti-oxydante du jus de pomme et du marc. Matériel et méthodes. Les expériences ont été réalisées avec deux variétés de pomme, une variété ancienne toscane, Panaia-rouge, et une variété commerciale, Golden Delicious. L'activité anti-oxydante a été évaluée au moyen de deux tests in vitro : la réactivité avec le radical libre DPPH•, et l'inhibition de la nitration de la tyrosine induite par le peroxynitrite (ONOO − ). Les analyses de jus ont été effectuées immédiatement après production et après 2 semaines de stockage à températures différentes : +4 • C, -20 • C, ou à température ambiante après pasteurisation. Résultats et discussi...

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“…In the last decade, the beneficial properties of phytochemicals have lead to a vigorous search for novel antioxidants from natural sources, involving the nutritional, pharmacological and medicinal chemistry fields [3][4][5][6][7][8][9][10][11][12][13][14][15][16], with particular emphasis on the prevention of cancer and cardiovascular distress through the consumption of this kind of nutraceuticals in the daily diet [17][18][19][20]. Accordingly, special attention has been paid to phenolic acids, anthocyanins, coumarins, tannins and flavonoids (including flavones and isoflavones), the latter being the largest group among phytochemicals [21].…”

Section: Introductionmentioning

confidence: 99%

A conformational study of hydroxyflavones by vibrational spectroscopy coupled to DFT calculations

Machado

Carvalho

Otero

et al. 2013

Spectrochimica Acta Part A: Molecular and Biomolecular Spectros

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This article appeared in a journal published by Elsevier. The attached copy is furnished to the author for internal non-commercial research and education use, including for instruction at the authors institution and sharing with colleagues.Other uses, including reproduction and distribution, or selling or licensing copies, or posting to personal, institutional or third party websites are prohibited. The conformational preferences of a series of hydroxyflavones were studied by Raman and FTIR spectroscopies, coupled to Density Functional Theory calculations. Special attention was paid to the effect of hydroxyl substitution, due to its importance on the biological activity of these compounds. Their conformational preferences were found to be determined mainly by the orientation of the hydroxylic groups at C 7 and within the catechol moiety, leading to the occurrence of distinct conformers in the solid state. A complete assignment of the experimental spectra was carried out for these molecules, in the light of their most stable conformers and the corresponding predicted vibrational pattern.

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Phytochemicals: nutraceuticals and human health

Abstract: Phytochemicals, as plant components with discrete bio-activities towards animal biochemistry and metabolism are being widely examined for their ability to provide health bene®ts.

Cited by 411 publications

References 68 publications

Moringa oleifera: a food plant with multiple medicinal uses

Moringa oleifera: a food plant with multiple medicinal uses

Phenolic profile and antioxidant activity in apple juice and pomace: effects of different storage conditions

A conformational study of hydroxyflavones by vibrational spectroscopy coupled to DFT calculations

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