Phytochemistry and Antimicrobial Property of Fruits of &lt;i&gt;Chrysophyllum albidum &lt;/i&gt;against Selected Clinical Isolates

Adeleye, S. A.; Orji, Chimere C.; Braide, W.; Akaluka, Cynthia K.

doi:10.56431/p-i0i4zs

Cited by 5 publications

(8 citation statements)

References 6 publications

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“…The zones of inhibition expressed by Escherichia coli at different concentrations ranged between 10 mm and 22 mm, Salmomella typhi (10 mm and 19 mm), Klebsiella pneumoniae (10 mm and 20 mm), Proteus vulgaris (10 mm and 19 mm) and Proteus mirabilis (10 mm and 16 mm). This affirmed the previous work on the antibacterial potentials of this plant (Duyilemi and Lawal, 2009;Adeleye et al, 2016;George et al, 2018). Thus, the leaf extract of C. albidum could serve as a pointer towards the development of drugs of natural origin to combat the infections caused by these pathogens and reduced or prevent death of patients.…”

Section: Discussionsupporting

confidence: 85%

Evaluation of Antibacterial and Antioxidant Properties of Leaf Extract of Chrysophyllum Albidum Against Selected Enteric Bacterial Pathogens

Odewade¹,

Odewade²

2023

FJS

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This study investigated the antibacterial and antioxidant potentials of Chrysophyllum albidum leaf extract against selected enteric bacterial pathogens (Escherichia coli, Klebsiella pneumoniae, Shigella dysenteriae, Salmonella typhi, Proteus mirabilis and Proteus vulgaris). Fresh leaves of Chrysophyllum albidum were shade air-dried and ground into fine powder. Thereafter, the leaves powder was cold extracted using methanol and sterile distilled water in ratio 3:2(v/v). The mixture obtained was concentrated in vacuo using a rotary evaporator and lyophilized. The crude extract was screened for antibacterial, phytochemicals and antioxidant properties. The antibacterial properties were determined using agar well diffusion and agar dilution methods while the antioxidant and phytochemical assay were analyzed using standard methods. The phytochemical screening of the extract revealed the presence of tannins, alkaloids, flavonoids, saponins, steroids, terpenoids, reducing sugar and cardiac glycosides. The zones of inhibition shown by the extract at 10 mg/mL against the bacterial isolates ranged between 10 mm and 22 mm. The highest zone of inhibition (22 mm) was expressed against Escherichia coli at a concentration of 10 mg/mL. The MICs ranged between 1.25 mg/mL and 5mg/mL while MBCs ranged between 2.5 mg/mL and 10 mg/mL. The antioxidant assay of leaf extract showed appreciable antioxidant potential when compared with ascorbic acid used as standard. The leaf extract exhibited percentage of 92.03% at a concentration of 500 µg/mL while ascorbic acid exhibited percentage of 96.54% at the same concentration. This study, therefore showed that leaf extract of Chrysophyllum albidum exhibited significant antibacterial and antioxidant activities against the test isolates.

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Section: Discussionsupporting

confidence: 85%

Evaluation of Antibacterial and Antioxidant Properties of Leaf Extract of Chrysophyllum Albidum Against Selected Enteric Bacterial Pathogens

Odewade¹,

Odewade²

2023

FJS

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“…According to the previous study [27], the extracts of the seeds and roots of C. albidum have anti-inflammatory, antidiarrheal and antihemorrhoidal activities, suggesting its potential use as home remedies and herbal treatments. Comparative study was carried out previously on the extraction of the phytochemical from C. albidum fruit [28]. The phytochemical tests indicated the presence of flavonoids, alkaloids, tannins, steroids, anthraquinone, as well as cardiac glycoside [28].…”

Section: Discussionmentioning

confidence: 99%

“…Comparative study was carried out previously on the extraction of the phytochemical from C. albidum fruit [28]. The phytochemical tests indicated the presence of flavonoids, alkaloids, tannins, steroids, anthraquinone, as well as cardiac glycoside [28]. The antimicrobial properties of the extract were examined on Escherichia coli, S. aureus, Klebsiella pneumonia, along with Candida albicans [28].…”

Section: Discussionmentioning

confidence: 99%

Antibacterial activity of Chrysophyllum albidium seed oil extract on pathogenic Staphylococcus aureus

Onuigbo,

Ukegbu,

Uzoigwe

2023

Narra X

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Antimicrobial resistance in Staphylococcus aureus has continued to rise and has become a general medical problem. Thus, the objective of this study was to use the Chrysophyllum albidum seed extract as an antibiotic against pathogenic Staphylococcus aureus. The antimicrobial impact of Chrysophyllum albidum seed oil on pathogenic Staphylococcus aureus from various sources were explored utilizing agar well dissemination strategy. The oil was separated utilizing the Soxhlet extraction strategy with n-hexane as the solvent. The oil extract was then prepared in various concentrations (62.5–500 mg/mL) and tested against three different pathogenic isolates of Staphylococcus aureus. At the highest concentration (500 mg/mL), the oil extract yielded 22–24.6 mm inhibition zones. Meanwhile, at the lowest concentration (62.5 mg/mL), the inhibition zones achieved were 14.6–16 mm. The minimum inhibitory concentration was 125 mg/mL, while the mean minimum bactericidal concentration was 250 mg/mL. In conclusion, our data suggested that the oil from seeds of Chrysophyllum albidum has antibacterial activities against Staphylococcus aureus and this needs to be further studied.

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“…It is reported as an excellent source of vitamin C, iron [65]. It is also known to be rich in minerals especially K (potassium) and Mg (magnesium) [66,67]. According to Okoli an Okere [68], African star apple is a rich source of anti-inflammatory and anti-hemorrhoidal compounds.…”

Section: Food Insecurity Mitigating Strategies-role Of Indigenous Cropsmentioning

confidence: 99%

Mitigating Global Food and Nutritional Insecurity: Role of Indigenous Crops

Tandoh¹,

Idun²,

Bemanu³

2023

Landraces - Its Productive Conservation in Animals and Plants

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Indigenous plants adapt well to marginal conditions, a situation that is essential for resilient agriculture and sustainable food systems in a rapidly changing global climate. These plants are known to be highly nutritious containing a wide array of antioxidants from their various parts including the leaves, stems, roots, branches, flowers etc. Polyphenols, flavonoids, isoflavonoids are major examples of these antioxidants which are chiefly found in many indigenous fruits, vegetables, nuts and seeds. The cultivation of these crops creates employment, providing a unique hotspot for biodiversity conservation as well as providing raw materials for most industries in the world. This review has also provided particular uses of these crops and their potential to combat food insecurity. The rapid exploitation of these crops and the lack of knowledge on their conservation is a major problem to global nutritional and food insecurity. Additionally, the rapid growth in population and technology will significantly impact the productive uses of these vital species. It is therefore crucial to provide a comprehensive review on the role of some of these plants in combating the food security issues globally.

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Phytochemistry and Antimicrobial Property of Fruits of <i>Chrysophyllum albidum </i>against Selected Clinical Isolates

Cited by 5 publications

References 6 publications

Evaluation of Antibacterial and Antioxidant Properties of Leaf Extract of Chrysophyllum Albidum Against Selected Enteric Bacterial Pathogens

Evaluation of Antibacterial and Antioxidant Properties of Leaf Extract of Chrysophyllum Albidum Against Selected Enteric Bacterial Pathogens

Antibacterial activity of Chrysophyllum albidium seed oil extract on pathogenic Staphylococcus aureus

Mitigating Global Food and Nutritional Insecurity: Role of Indigenous Crops

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