Phytochemistry and pharmacology ofTecomella undulata

Abstract

Tecomella undulata (Bignoniaceae) is a monotypic genus and one of the most important deciduous, ornamental shrub or small tree of the acrid zone of India. Locally known as Rohida, Roheda in Hindi, Rakhtroda in Marathi, Dadimacchada, Chalachhada, Dadimapuspaka in Sanskrit mostly found in the Thar desert regions of India and Pakistan. The plant holds tremendous potential of medicinal value and is used in traditional and folklore system of medicines. It has been used traditionally in various ailments like syphilis, swelling, leucorrhoea and leucoderma, enlargement of spleen, obesity, tumours, blood disorders, flatulence and abdominal pain. Tecomella undulata has gained prominence due to presence of some prominent secondary metabolites of great therapeutic potential like stigmasterol, β-sitosterol, α-lapachone, tectol isolated from heartwood, bark and leaf. The present review presents the traditional information and recent scientific update on this plant with therapeutic potential.

High Serum Level of Matrix Metalloproteinase-1 (MMP-1) Correlates Positively with The Severity of Photoaging Facial Wrinkles

“…With age, a decrease in elastin, collagen, and hyaluronic acid causes skin strength and flexibility loss, resulting in wrinkles. [6,9] External factors are still the most influential factor in the process of wrinkling. These external factors can be exposure to UV rays, unhealthy lifestyles, environmental pollution, radiation, cigarette smoke, and stress.…”

“…The increase in MMP-1 levels was around 4.4 ± 0.2 times compared to skin that was not exposed to UV radiation [4]. Matrix metalloproteinase-1 was chosen in this study because it is a subgroup of MMPs that play a role important in the photoaging processing collagenase with degradation of collagen types 1 and 2 resulting from direct UVA and UVB exposure with significantly increased regulation of these exposures compared to other types of MMPs, and most markedly increased when skin severity is present [6][7][8].…”

Characterization and anti-aging effects ofOpuntia ficus-indica(L.) Miller extracts in ad-galactose-induced skin aging model

“…5,6 Several studies have reported that oxidative stress and the overproduction of reactive oxygen species (ROS) play an important role in the skin aging process. 2,7,8 The excessive exposure of skin to UV radiation can lead to the over-production of ROS, which in turn triggers the activity of enzymes such as elastase, collagenase, and other matrix metalloproteinases (MMPs). These enzymes are responsible for the degradation of the skin's extracellular matrix proteins such as collagen and elastin, which leads to the appearance of skin wrinkles and loss of skin flexibility and strength.…”

Effect of <i>Punica granatum</i> and <i>Tecomella undulata</i> supplementation on nutrient utilization, enteric methane emission and growth performance of Murrah male buffaloes

“…Its peel, covering around 60% of fruit, is a rich source of ellagitannins, flavonoids and proanthocyanidin (Mirdehghan and Rahemi, 2007). Tecomella undulata, a deciduous shrub has tremendous medicinal and therapeutic potential (Rohilla and Garg, 2014), which is attributed to the presence of secondary metabolites (phytosterols, glycosides, tannins, phenolic compounds, flavonoids, saponins) in its heartwood, bark and leaf (Dhir and Shekhawat, 2012).…”