Phytochemistry and Pharmacology of Medicinal Plants Used by the Tenggerese Society in Java Island of Indonesia

Abstract

The archipelagic country of Indonesia is inhabited by 300 ethnic groups, including the indigenous people of Tengger. Based on the reported list of medicinal plants used by the Tengger community, we have reviewed each of them for their phytochemical constituents and pharmacological activities. Out of a total of 41 medicinal plants used by the Tengerrese people, 33 species were studied for their phytochemical and pharmacological properties. More than 554 phytochemicals with diverse molecular structures belonging to different chemical classes including flavonoids, terpenoids, saponins and volatiles were identified from these studied 34 medicinal plants. Many of these medicinal plants and their compounds have been tested for various pharmacological activities including anti-inflammatory, antimicrobial, wound healing, headache, antimalarial and hypertension. Five popularly used medicinal plants by the healers were Garcinia mangostana, Apium graveolens, Cayratia clematidea, Drymocallis arguta and Elaeocarpus longifolius. Only A. graviolens were previously studied, with the outcomes supporting the pharmacological claims to treat hypertension. Few unexplored medicinal plants are Physalis lagascae, Piper amplum, Rosa tomentosa and Tagetes tenuifolia, and they present great potential for biodiscovery and drug lead identification.

Etnofarmasi Pada Pengobat Tradisional di Kabupaten Ngawi: Upaya Pelestarian Pengetahuan Jamu Cekok

“…Dalam satu dasawarsa terakhir, penelitian etnofarmasi telah banyak dilakukan pada masyarakat lokal di Jawa Timur, antara lain: Suku Tengger [15][16][17][18][19][20][21], Suku Madura [22,23], Suku Osing [24], dan Suku Jawa di lereng Gunung Wilis [25]. Hanya beberapa studi yang berfokus menginventarisasi pengetahuan tradisional Jamu Cekok, yang dilakukan di Yogyakarta [13] dan Kabupaten Wonogiri, Jawa Tengah [26].…”

Ethnopharmacology of medicinal plants used by the Tenggerese community in Bromo Tengger Semeru National Park, Indonesia

“…The Tengger people have a profound understanding and utilization of various medicinal plants, which play a pivotal role in their primary healthcare (Bhagawan et al 2023). Their ethnopharmacological knowledge has been passed down through generations, upheld by the priesthood of traditional leaders (dukun pandhita), traditional healers (dukun cilik), and the Tengger community itself, actively engaging in independent traditional medicine (Nugraha et al 2022;Putri et al 2022). However, the relentless cultural influences from external sources have led to rapid environmental and cultural transformations in the region.…”

O uso de fitoterápicos no manejo da cefaleia

“…Andrade (2021), foram examinados os benefícios da administração dos extratos de gengibre (Zingiber officinale) na redução dos sintomas da enxaqueca, em pacientes que não faziam uso da terapia convencional, através da análise de ensaios clínicos randomizados. O artigo evidenciou que não há recomendações clínicas seguras quanto ao manejo do poucas evidências, embora apresente efeitos benéficos na mitigação da dor e das náuseas associadas à enxaqueca.JáNugraha et al (2022) analisou os componentes químicos e atividades farmacológicas de algumas plantas medicinais aplicadas na comunidade de Tengger, na Indonésia, incluindo o gengibre (Zingiber officinale) e a cúrcuma (Curcuma longa). Segundo o artigo, a ingestão de gengibre na alimentação de pacientes com cefaleia primária reduziu a intensidade das crises de enxaqueca e a cúrcuma diminuiu a intensidade dos sintomas de dor de cabeça.Ademais, o uso de Xanthium strumarium L.(FAN et.al., 2019) e de sementes de Cassia obtusifolia L. (ALI; PARK; CHANG, 2021) foi relatado para manejo de dores de cabeça pela medicina tradicional chinesa há vários anos.…”