Phytochemistry and therapeutic effects of Alhagi spp. and tarangabin in the Traditional and modern medicine: a review

Abstract

Alhagi maurorum is one of the species of Alhagi genus producing manna of Tarangabin. Tarangabin is mainly prepared in Iran and Afghanistan. The medicinal properties of Tarangabin and A. maurorum have been mentioned in some major Materia Medica manuscripts in the Islamic era. Tarangabin has various pharmacological properties including antioxidant, anti-inflammatory, antipyretic, diaphoretic, diuretic, expectorant, analgesic and gastrointestinal effects. The purpose of this review is to introduce Alhagi plant and its different species, to present its geographical distribution, and to review its phytochemical and pharmacological properties as well as traditional and folklore applications. Phytochemistry of different parts of Alhagi, such as root, leaf and manna is also explained in details. In addition, temperament and medicinal uses of Tarangabin mentioned in the Islamic traditional medicine (ITM) books are presented. Indeed, sparse clinical research has been done on the medicinal properties of Tarangabin, which calls for future well-designed trials.

Traditional Uses, Chemistry, Pharmacology, Toxicology and Quality Control of Alhagi sparsifolia Shap.: A Review

“…A. sparsifolia belongs to class II wet-heat drugs in the Uyghur system of medicine, in which drugs exhibiting antihypertensive, anticancer, and antidiabetic effects are included; however, no scientific experiments have been designed to prove these effects. The urinary tract effect, antipyretic effect, musculoskeletal effect and cardiac effect have been already investigated in other plants of the same genus, but so far no similar activity has been reported in this plant and the studies of similar activity are the focus of future research on this plant ( Tavassoli, 2020 ). Chronic toxicity tests reveal the safety and nontoxicity of A. sparsifolia ; however, this evidence may be insufficient.…”

UPLC-PDA-MS/MS Profiling and Healing Activity of Polyphenol-Rich Fraction of Alhagi maurorum against Oral Ulcer in Rats

“…In Egypt and Afghanistan, A. maurorum is used to treat gastrointestinal, liver, and urinary tract disorders [ 15 ]. It is traditionally recommended for treatment of progressive ulcers, hemorrhoids, cough, rheumatic pain, angina, eczema, and gastritis in Pakistan, Uzbekistan, and Saudi Arabia [ 16 ].The manna of Alhagi is reported in the Islamic traditional medicine (ITM) books for its laxative, detergent, and antipyretic properties, and as a cure for cough and liver bile diseases [ 16 ]. The crude extract of A. maurorum aerial parts exhibited a protective effect against peptic ulcers and gastroesophageal reflux in rats [ 17 ].…”

Alhagi kirghisorum: Technological Aspects of its Thick Extract for the Pharmaceutical Application

“…Infusions, decoctions or fresh juice are taken for the treatment of gastrointestinal diseases, mainly chronic diarrhea and dysentery. Extracts from the aerial parts of camelthorn have an antimicrobial effect, and they exert a pronounced bactericidal effect on streptococci, staphylococci, and dysentery rods (Ahmad et al, 2010;Neamah, 2012;Asghari et al, 2016;Tavassoli et al, 2020). Decoctions are successfully used in the form of throat rinses in acute tonsillitis.…”