Phytoconstituent Screening and Antibacterial Activity of the Leaf Extracts from &amp;lt;i&amp;gt;Canarium odontophyllum&amp;lt;/i&amp;gt; Miq.

Basri, Dayang Fredalina; Nor, Nur Hafidzah Mohd

doi:10.4236/ajps.2014.519303

Cited by 18 publications

(21 citation statements)

References 23 publications

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“…The MIC value revealed that the minimum concentration of the plant extract to inhibit S. aureus was 6.25 mg/mL while E. coli showed 12.5 mg/mL. Contradict to our findings, Basri and Mohd Nor (2014) had exhibited MIC values with 0.391 mg/mL for both acetone and methanol extracts for Canarium odontophyllum leaves against S. aureus via similar method. In addition, two previous studies by Eloff (2004) and Kuete (2010) had purported that the best MIC value is lower than 0.1 mg/mL.…”

Section: Discussionsupporting

confidence: 73%

Qualitative Phytochemical Analysis and Antimicrobial Activity of Piper sarmentosum Leaves Extract Against Selected Pathogens

Yusof

Radzi

Richard

2019

JSKM

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The controversial usage of antiseptic in treating wound infections had become a huge issue over the years due to its minimal effectiveness and high toxicity level that are harmful to humans. Hence, numerous studies had been carried out to determine other possible approaches including herbal remedies. The alarming situation had led us to study on Piper sarmentosum and its antimicrobial activity against selected pathogens. In present study, methanol extract of Piper sarmentosum leaves were prepared to investigate the presence of phytochemical compounds. The in vitro antimicrobial activity of crude methanolic extract was evaluated using disc diffusion and microdilution broth methods. The study demonstrated the antimicrobial activity of leaves extract against Staphylococcus aureus (7 mm) and Escherichia coli (6.5 mm). However, no zone of inhibition was observed against Pseudomonas aeruginosa. Meanwhile, the MIC values for Staphylococcus aureus was 6.25 mg/mL whilst Escherichia coli was 12.5 mg/mL. In addition, the phytochemical screening results revealed that the extract contained glycosides, flavonoids, terpenoids, alkaloids and phenolics. In conclusion, methanolic extract of Piper sarmentosum leaves has the potential as a new, effective alternative towards current drugs that are available for skin-associated infection. The findings from this study are crucial in providing latest information of the plant's additional values that can be incorporated as a baseline for current and future studies as well as in investigating other possible plants that are beneficial for health purposes, particularly for combating skin-associated infection.

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Section: Discussionsupporting

confidence: 73%

Qualitative Phytochemical Analysis and Antimicrobial Activity of Piper sarmentosum Leaves Extract Against Selected Pathogens

Yusof

Radzi

Richard

2019

JSKM

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“…From the disc diffusion assay, the methanol and acetone extracts showed high activity towards S.aureus that can be observed from the larger size of the zone of inhibition on agar plates. This is supported by Basri & Nor (2014) who reported the methanol and acetone extracts from the leave of C. odontophyllum were capable of inhibiting the growth of S. aureus. Other than that, the leave extract from another species C. schwenfurthii act as an antibacterial agent against S. aureus (Odunkabu & Ganiyu 2012).…”

Section: Screening Of Antimicrobial Activitymentioning

confidence: 59%

Stem Bark of Canarium odontophyllum Miq. (Dabai) as Potential Source of Antimicrobial Agent

Basri

Mustari

Alamin

et al. 2017

JSKM

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and Fusarium solani M2781. The extracts from C. odontophyllum stem bark from 3.125 mg/ml to 25 mg/ml were screened against the tested microorganisms using disc diffusion method. The Minimum inhibitory concentration (MIC) and Minimum Bactericidal Concentration (MBC) of the extracts against susceptible organisms were determined using microbroth dilution method and streak-plate technique, respectively. From the antibacterial screening assay, the growth of S. aureus, B. cereus and A. baumannii were inhibited by methanol extract whereas the acetone extract was capable of inhibiting all the tested microorganisms except E.coli, F. solani and A. niger. The lowest MIC value for methanol extract was against A. baumannii (0.195 mg/ml) whereas its MBC value was twice its MIC value (0.391 mg/ml), indicating that methanol extract was bacteriostatic against A. baumannii. While for acetone extract, S. aureus showed bactericidal effect with equal MIC and MBC values at 0.195 mg/ ml. In conclusion, stem bark of C. odontophyllum has the potential to be the source of antibacterial agent and can be exploited as an alternative phytoantimicrobial.

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“…The antimicrobial activity was screened by both agar well diffusion (Basri and Nor, 2014) and agar disc diffusion method (Valgas et al, 2007) ). Four wells of 5 mm diameter were made at least 1.5cm from edge of the plate.…”

Section: Screening Of Antibacterial Activity (Evaluation Methods)mentioning

confidence: 99%

Antibacterial Effects of Thuja Leaves Extract

Sah

Regmi

Tamang

2017

Int J Appl Sci Biotechnol

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Various medicinal plants are common in use in Nepal for the treatment of different diseases. Nowadays, drug resistance has emerged as a major problem for various infections, in such case plants can be used as alternative for the production of new antimicrobial agents. Thuja (in Nepali: dhupi) is a small evergreen genus of the Cupressaceae family. This species is widely cultivated as a common ornamental plant in Nepal and India. This study examined the antibacterial activity of Thuja leaves extract on gram positive (Staphylococcus aureus and Streptococcus spp.) and gram-negative bacteria (E. coli and Pseudomonas aeruginosa). Thuja leaves were collected from different localities of Dharan, and dried under shade for 10 days. They were then grinded using mechanical grinder. Leaf extract (oleoresin) was obtained by soxhlet extraction technique using mixture of Ethyl acetate, Ethanol and chloroform in the ratio 40:30:30 as the solvent. The antibacterial activity of Thuja oleoresin was tested using both Agar well diffusion as well as disc diffusion technique. Minimum Inhibitory Concentration(MIC) was determined by agar well diffusion on MHA plates. Thuja oleoresin showed distinct antibacterial activity towards all four isolates on both agar well and disc diffusion methods. MIC for Pseudomonas aeruginosa and Streptococcus spp. was found to be 12.5 µl whereas for E. coli and Staphylococcus aureus, MIC was 25 µl. Thus from our results, it is concluded that Thuja leaves have antibacterial effects and can be a potential source for production of antibacterial drugs.

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Phytoconstituent Screening and Antibacterial Activity of the Leaf Extracts from <i>Canarium odontophyllum</i> Miq.

Cited by 18 publications

References 23 publications

Qualitative Phytochemical Analysis and Antimicrobial Activity of Piper sarmentosum Leaves Extract Against Selected Pathogens

Qualitative Phytochemical Analysis and Antimicrobial Activity of Piper sarmentosum Leaves Extract Against Selected Pathogens

Stem Bark of Canarium odontophyllum Miq. (Dabai) as Potential Source of Antimicrobial Agent

Antibacterial Effects of Thuja Leaves Extract

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