1984
DOI: 10.1111/j.1550-7408.1984.tb04311.x
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Phytohemagglutinin Induces Delays in Oral Regeneration in the Ciliate Stentor coeruleus1

Abstract: Regenerating Stentor, exposed to the plant lectin phytohemagglutinin, are significantly delayed in completing oral regeneration. All of the delays are restricted to the earliest stages of regeneration prior to stage 3. The effects of phytohemagglutinin are reversible once the drug is removed. The addition of the presumed sugar receptor for phytohemagglutinin, N-acetylgalactosamine, at the start of oral regeneration could not reverse the effects of phytohemagglutinin, but the addition of excess (10 mM) extracel… Show more

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Cited by 4 publications
(7 citation statements)
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“…The same effect of extracellular calcium is also observed with PHA (Maloney, 1984). These results suggest that Con A is not stimulating calcium influx as it does in lymphocyte mitogenesis since one would predict that the excess extracellular calcium should increase the delays if this were true.…”
Section: Discussionsupporting
confidence: 78%
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“…The same effect of extracellular calcium is also observed with PHA (Maloney, 1984). These results suggest that Con A is not stimulating calcium influx as it does in lymphocyte mitogenesis since one would predict that the excess extracellular calcium should increase the delays if this were true.…”
Section: Discussionsupporting
confidence: 78%
“…Based on these results with Con A and the earlier results from this lab with PHA (Maloney, 1984) and local anesthetics (Maloney, 19801, there is clearly some relationship between calcium metabolism, membrane disturbance and oral regeneration. In almost all cases the presence of excess extracellular calcium can negate the effects of a particular agent on oral regeneration, suggesting the necessity of extracellular calcium for normal oral regeneration.…”
Section: Discussionmentioning
confidence: 64%
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