The study samples were collected during the months of April and May 2022, samples were collected from different regions in Diyala Governorate -Iraq. The study aimed to assess the role of oleander plant in the phytoremediation of heavy metals (lead , cadmium , arsenic and selenium) within Diyala Governorate by estimating their concentration in the leaves of the plant and the soil on which it grows as well as calculating the bioaccumulation factor (BAF). Al-Muqdadiyah Industrial area was one of the most polluted areas with lead, the highest concentration of lead appeared in the leaves of the oleander plant grown in this area, as well as the soil on which it grows (2.452 and 0.904 ) ppm respectively. The highest concentration of cadmium was recorded for oleander leaves in the old city of Baqubah (2.208ppm), while the highest concentration appeared in the soil on which it grows in the Al-Muqdadiyah Industrial area (0.363ppm). The Al-Muqdadiya industrial area also recorded the highest concentration of arsenic in the leaves of the oleander plant ( 0.559 ppm) ,but the highest concentration in the soil on which it grows was in the central city of Al-Muqdadiyah (0.218ppm) , followed by the industrial city off Al-Muqdadiyah.( 0.132ppm) . The highest concentration of selenium appeared in the industrial city of Al-Muqdadiya in both the leaves of the oleander plant and the soil on which it grows (0.441 and 0.104) ppm. The value of the bioaccumulation factor (BAF) shows the efficiency of the oleander plant in the phytoremediation of cadmium, followed by lead, arsenic and selenium in varying proportions.