Phytosynthesis of nanoparticles: concept, controversy and application

Husen, Azamal; Siddiqi, K. S.

doi:10.1186/1556-276x-9-229

Cited by 344 publications

(159 citation statements)

References 179 publications

(195 reference statements)

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“…It is identified that 15% of product on a global market is having some kind of nanotechnology incorporated during processing, and it is expected to reach US $ 1 trillion (Husen and Siddiqi 2014). There are several sources used for synthesis of nano particles such as, noble metals, i.e.…”

Section: Introductionmentioning

confidence: 99%

Silver nano fabrication using leaf disc of Passiflora foetida Linn

Lade

Patil

2017

Appl Nanosci

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The main purpose of the experiment is to develop a greener low cost SNP fabrication steps using factories of secondary metabolites from Passiflora leaf extract. Here, the leaf extraction process is omitted, and instead a leaf disc was used for stable SNP fabricated by optimizing parameters such as a circular leaf disc of 2 cm (1, 2, 3, 4, 5) instead of leaf extract and grade of pH (7, 8, 9, 11). The SNP synthesis reaction is tried under room temperature, sun, UV and dark condition. The leaf disc preparation steps are also discussed in details. The SNP obtained using (1 mM: 100 ml AgNO 3 ? singular leaf disc: pH 9, 11) is applied against featured room temperature and sun condition. The UV spectroscopic analysis confirms that sun rays synthesized SNP yields stable nano particles. The FTIR analysis confirms a large number of functional groups such as alkanes, alkyne, amines, aliphatic amine, carboxylic acid; nitro-compound, alcohol, saturated aldehyde and phenols involved in reduction of silver salt to zero valent ions. The leaf disc mediated synthesis of silver nanoparticles, minimizes leaf extract preparation step and eligible for stable SNP synthesis. The methods sun and room temperature based nano particles synthesized within 10 min would be use certainly for antimicrobial activity.

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Section: Introductionmentioning

confidence: 99%

Silver nano fabrication using leaf disc of Passiflora foetida Linn

Lade

Patil

2017

Appl Nanosci

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“…AgNP's is unique among other metal nanoparticles and have received significant attraction among researchers because of their specific physical, chemical, and biological properties and their applications in medicine, cosmetics, and biomedical devices. Furthermore, AgNP's have been reported for antibacterial and antifungal activities [16]. It also possesses low toxicity when compared to other nanoparticles.…”

Section: Resultsmentioning

confidence: 99%

Anti-Inflammatory Activity of Syzygium Aromaticum Silver Nanoparticles: In Vitro and in Silico Study

Varghese

Ragavan

Sivaraj

et al. 2017

Asian J Pharm Clin Res

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Objective: In the present study, antioxidant and anti-inflammatory activity of Syzygium aromaticum (clove) silver nanoparticles (clove AgNP's) was evaluated.Methods: Gas chromatography-mass spectrometry technique was used to identify the compounds present in the aqueous extract of clove. Fourier transform infrared (FT-IR) analysis was done to characterize the clove silver AgNP's. 1,1-diphenyl-2-picrylhydrazyl (DPPH) assay was performed to evaluate the antioxidant property of nanoparticles (0.05 and 0.25 mg/ml) and aqueous extracts (0.05, 0.1, and 0.25 mg/ml) of clove. The antiinflammatory property of the clove AgNP's was determined by inhibition of protein denaturation and downregulation of interleukin-1 beta. In silico molecular docking studies was performed using Schrodinger Maestro software. Results:Eugenol was found to be highest with 16.27%. The AgNP's exhibited dose-dependent antioxidant property. AgNP's scavenged 80% of radical at the concentration of 0.25 mg/ml. The scavenging activity of AgNP's markedly increased when compared to aqueous extract at the same concentration. Inhibition of protein denaturation assay also revealed AgNP's showing the highest activity (66%) when compared with drug aspirin (55%) and aqueous extract (56%). In the enzyme-linked immunosorbent assay (ELISA) method, AgNP's showed better inhibition (80%) when compared to aqueous extract (60%). Among 15 compounds, two compounds (eugenol and methyl 14-methylpentadecanoate) showed good glide energy, docking score, and hydrogen-bonded active site interactions with the protein interleukin-1 beta. Conclusion:As AgNP's were more active than the aqueous extract, it may be considered for pharmacological activity against inflammatory disorders.

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“…It is expected that in the near future over 15 % of all products at the world market will certainly include nanotechnology in their production process [37]. Designed nanoparticles (1 to 100 nm) may possess different physical and chemical properties than those found in nature; and their impact on human health must be evaluated based on their size and shape [27,49,62,88].…”

Section: Abstract: Nanoparticles Cerium Dioxide Biotransformation mentioning

confidence: 99%