2005
DOI: 10.1021/jf0508044
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Phytotoxic Activity of Bibenzyl Derivatives from the Orchid Epidendrum rigidum

Abstract: A whole plant chloroform-methanol extract of the orchid Epidendrum rigidum inhibited radicle growth of Amaranthus hypochondriacus seedlings (IC50 = 300 microg/mL). Bioassay-guided fractionation furnished four phytotoxins, namely, gigantol (1), batatasin III (2), 2,3-dimethoxy-9,10-dihydrophenathrene-4,7-diol (9), and 3,4,9-trimethoxyphenanthrene-2,5-diol (11), along with the known flavonoids apigenin, vitexin, and isovetin and the triterterpenoids 24,24-dimethyl-9,19-cyclolanostane-25-en-3beta-ol (14) and 24-m… Show more

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Cited by 54 publications
(27 citation statements)
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“…The phytotoxicity of 1, 10 and 11 against both Amaranthus hypochondriacus and Lemna paucicostata have been investigated by Mata and co-workers. 38 In their study 1, 10 and 11 displayed a pronounced phytotoxic effect and caused increased cellular leakage.…”
mentioning
confidence: 92%
“…The phytotoxicity of 1, 10 and 11 against both Amaranthus hypochondriacus and Lemna paucicostata have been investigated by Mata and co-workers. 38 In their study 1, 10 and 11 displayed a pronounced phytotoxic effect and caused increased cellular leakage.…”
mentioning
confidence: 92%
“…Other Asian countries such as Indonesia, Malaysia, Taiwan, Singapore, Vietnam, Shri Lanka, Thailand, Myanmar, etc. have been using orchids in traditional medicine since the ancient time till date (Basu et al, 1971;Kumar et al, 2000;Hernández-Romero et al, 2005;Luo et al, 2007).…”
Section: Introductionmentioning
confidence: 99%
“…Some of the isolated compounds have been evaluated for biological properties and significant results were reported. Examples are the inhibition of ephemeranthoquinone on the spontaneous contraction of the guinea-pig ileum, spasmolytic, allelopathic and inhibitory activities of batatasin III on germination and radicle growth, and cytotoxicity of tristin against human stomach cancer SGC-7901 [6,[14][15][16][17][18][19].…”
Section: Discussionmentioning
confidence: 99%