Picking up and placing a liquid marble using dielectrophoresis

Ooi, Chin Hong; Jin, Jing; Nguyen, Anh V.; Evans, Geoffrey M.; Nguyen, Nam‐Trung

doi:10.1007/s10404-018-2163-0

Cited by 31 publications

(19 citation statements)

References 53 publications

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“…There are several actuation schemes for sessile and floating LMs, including utilizing environmental changes such as temperature [25], pH [26], and irradiation [27], and being driven by external fields. These external fields are controllable electric [28][29][30][31][32][33], magnetic [22][23][24], and acoustic [34,35] fields and gravitational field [36]. We have successfully demonstrated the use of dielectrophoretic (DEP) force to move sessile [29,30] and floating LMs [31] in a nonuniform electric field.…”

Section: Introductionmentioning

confidence: 99%

Dielectrophoretic Trapping of a Floating Liquid Marble

et al. 2019

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A liquid marble, a liquid droplet coated with hydrophobic powder, is an emerging digital microfluidic platform. It can potentially serve as a mixer or reactor for chemical and biological assays in the microscale. Automated manipulation of liquid marbles is essential for the implementation of more microfluidic functions in the technology platform of "lab in a marble". We report the analytical and experimental results of trapping a floating liquid marble using dielectrophoresis in a nonuniform electric field. Liquid marbles with volumes ranging from 5 to 50 μL are effectively trapped by the dielectrophoretic force from a horizontal distance ranging from 10 to 60 mm and under an applied voltage ranging from 1.6 to 5 kV. A one-dimensional analytical model is then proposed for the trapping process and agrees well with experimental data. Finally, based on the relationship between the static friction coefficient and the Bond number of a floating liquid marble, an operation map is derived for successful trapping of the liquid marble, providing a better insight into controlled manipulation of liquid marbles.

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Section: Introductionmentioning

confidence: 99%

Dielectrophoretic Trapping of a Floating Liquid Marble

et al. 2019

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“…Conventional liquid marbles possess reasonably good mechanical strength [12][13][14][15]. Moreover, the generation [16,17] and manipulation [18][19][20][21][22][23][24][25][26] of liquid marbles have been relatively well developed for other applications. In fact, significant advances in cell biology, bio-engineering, and bio-medicine have been made using liquid marbles as bio-reactors [27][28][29][30][31].…”

Section: Introductionmentioning

confidence: 99%

Core-Shell Beads Made by Composite Liquid Marble Technology as A Versatile Microreactor for Polymerase Chain Reaction

et al. 2020

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Over the last three decades, the protocols and procedures of the DNA amplification technique, polymerase chain reaction (PCR), have been optimized and well developed. However, there have been no significant innovations in processes for sample dispersion for PCR that have reduced the amount of single-use or unrecyclable plastic waste produced. To address the issue of plastic waste, this paper reports the synthesis and successful use of a core-shell bead microreactor using photopolymerization of a composite liquid marble as a dispersion process. This platform uses the core-shell bead as a simple and effective sample dispersion medium that significantly reduces plastic waste generated compared to conventional PCR processes. Other improvements over conventional PCR processes of the novel dispersion platform include increasing the throughput capability, enhancing the performance and portability of the thermal cycler, and allowing for the contamination-free storage of samples after thermal cycling.

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“…The combination of numerous interior liquids and coating particles can render liquid marbles with highly specific properties [15] . Liquid marbles are also highly versatile and can be manipulated using electrostatics, [16–19] magnetism, [20–22] thermal gradient, and surface tension gradient [23–25] . These properties enable tailor‐made microreactor platforms, making liquid marbles an excellent candidate for a microscale batch reactor.…”

Section: Introductionmentioning

confidence: 99%

Digital Imaging‐based Colourimetry for Enzymatic Processes in Transparent Liquid Marbles

et al. 2020

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Liquid marbles are a promising microreactor platform that recently attracts significant research interest owing to their ability to accommodate a wide range of micro reactions. However, the use of destructive and ex‐situ methods to monitor reactions impairs the potential of liquid‐marble‐based microreactors. This paper proposes a non‐destructive, in situ, and cost‐effective digital‐imaging‐based colourimetric monitoring method for transparent liquid marbles, using the enzymatic hydrolysis of starch as an illustrative example. The colourimetric reaction between starch and iodine produces a complex that exhibits a dark blue colour. We found that the absorbance of red channel of digital images showed a linear relationship with starch concentration with high sensitivity and repeatability. This digital‐imaging‐based colourimetric method was used to study the hydrolysis of starch by α‐amylase. The results show high accuracy and applicability of first‐order kinetics for this reaction. The demonstration of digital‐imaging‐based colourimetry indicates the potential of liquid marble‐based microreactors.

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Picking up and placing a liquid marble using dielectrophoresis

Cited by 31 publications

References 53 publications

Dielectrophoretic Trapping of a Floating Liquid Marble

Dielectrophoretic Trapping of a Floating Liquid Marble

Core-Shell Beads Made by Composite Liquid Marble Technology as A Versatile Microreactor for Polymerase Chain Reaction

Digital Imaging‐based Colourimetry for Enzymatic Processes in Transparent Liquid Marbles

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