Picture free recall performance linked to the brain's structural connectome

Coynel, David; Gschwind, Leo; Fastenrath, Matthias; Freytag, Virginie; Milnik, Annette; Spalek, Klara; Papassotiropoulos, Andreas; Quervain, Dominique J.‐F. de

doi:10.1002/brb3.721

Cited by 4 publications

(3 citation statements)

References 76 publications

(111 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…It is well‐established that successful memory retrieval requires the conjunct activation of a network of brain regions (Dickerson & Eichenbaum, 2010 ; Ritchey & Cooper, 2020 ; Rugg & Vilberg, 2013 ) further supporting the benefit of a higher interconnectedness and less functional segregation. Thus, these findings complement our previous results (Spalek et al, 2015 ) as well as existing literature (Coynel et al, 2017 ; Tunç et al, 2016 ) by providing a neuronal link for the observed memory advantage of females compared to males. Specifically, we previously identified differences between females and males in emotional episodic memory in a large sample (>3000 subjects).…”

Section: Discussionsupporting

confidence: 92%

“…The association between episodic memory and structural brain connectivity has so far been investigated mainly in relation with aging (Fjell et al, 2016 ). Only one study (Coynel et al, 2017 ) has investigated the association between individual episodic memory performance and the level of structural brain connectivity in healthy young subjects. Additionally, Tunç et al, 2016 were able to distinguish males from females using connectivity as well as behavioral classifiers (derived from performance on a neurocognitive battery including memory tasks).…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Sex‐dependent differences in connectivity patterns are related to episodic memory recall

Spalek,

Coynel,

de Quervain

et al. 2023

Human Brain Mapping

Self Cite

View full text Add to dashboard Cite

Previous studies have shown that females typically outperform males on episodic memory tasks. In this study, we investigated if (1) there are differences between males and females in their connectome characteristics, (2) if these connectivity patterns are associated with memory performance, and (3) if these brain connectome characteristics contribute to the differences in episodic memory performance between sexes. In a sample of 655 healthy young subjects (n = 391 females; n = 264 males), we derived brain network characteristics from diffusion‐weighted imaging (DWI) data using models of crossing fibers within each voxel of the brain and probabilistic tractography (graph strength, shortest path length, global efficiency, and weighted transitivity). Group differences were analysed with linear models and mediation analyses were used to explore how connectivity patterns might relate to sex‐dependent differences in memory performance. Our results show significant sex‐dependent differences in weighted transitivity (d = 0.42), with males showing higher values. Further, we observed a negative association between weighted transitivity and memory performance (r = −0.12). Finally, these distinct connectome characteristics partially mediated the observed differences in memory performance (effect size of the indirect effect r = 0.02). Our findings indicate a higher interconnectedness in females compared to males. Additionally, we demonstrate that the sex‐dependent differences in episodic memory performance can be partially explained by the differences in this connectome measure. These results further underscore the importance of sex‐dependent differences in brain connectivity and their impact on cognitive function.

show abstract

Section: Discussionsupporting

confidence: 92%

Section: Introductionmentioning

confidence: 99%

Sex‐dependent differences in connectivity patterns are related to episodic memory recall

Spalek,

Coynel,

de Quervain

et al. 2023

Human Brain Mapping

Self Cite

View full text Add to dashboard Cite

show abstract

“…Activity in this region is augmented for selective attention relative to predict behavioral outcome (Jor’dan et al ., 2017). Free recall performance also activates temporal pole and nucleus accumbens region, with some unique memory-specific connections (Coynel et al ., 2017). Moreover, the frontoparietal cortex and visual regions activities are greatest when changing task sets (Lamichhane et al ., 2020).…”

Section: Introductionmentioning

confidence: 99%

The effect of creative expression program in neurocognitive networks performance measured by task and resting-state functional MRI

Zhao

Cai

et al. 2023

International Psychogeriatrics

View full text Add to dashboard Cite

Background: The current study examined the effects of a 16-week creative expression program on brain activity during a story creating task and resting-state functional network connectivity in mild cognitive impairment (MCI) adults. Method: Thirty-six MCI adults were allocated to either the creative expression program (CrExp, n = 18) or control group (CG,n = 18). Before and after intervention, all participants were scanned with functional magnetic resonance imaging (fMRI) during story creating task performance and a resting state. The two-group comparison was calculated between the blood oxygenation level-dependent (BOLD) signal changes for each cluster to investigate the differences in fMRI activation and functional connectivity (FC) between two groups. Results: Task activation analyses showed an increase in the right anterior cingulate gyrus (ACG), right medial frontal gyrus (MFG), right lentiform nucleus (LN), left hippocampus (HIP), left middle occipital gyrus (MOG), and left cerebellum posterior lobe (CPL) (p < 0.05). Story creating performance improvements were associated with greater activation in the left HIP region. Resting-state functional connectivity (FC) between left HIP and certain other brain areas shown a significant interaction of creative expression group versus control group. Moreover, connectivity between the right angular gyrus (ANG), right inferior temporal gyrus (ITG), right superior occipital gyrus (SOG), left ANG, and left MFG were related to improved cognitive performance (p < 0.05). Conclusion: These data extend current knowledge by indicating that the creative expression program can improve cognitive activation in MCI, and these enhancements may be related to the neurocognitive network plasticity changes induced by creative expression training.

show abstract

Neuroanatomical Dysconnectivity Underlying Cognitive Deficits in Bipolar Disorder

McPhilemy

Nabulsi

Kilmartin

et al. 2020

Biological Psychiatry: Cognitive Neuroscience and Neuroimaging

View full text Add to dashboard Cite

Background: Graph theory applied to brain networks is an emerging approach to understand the brains' topological associations with human cognitive ability. Despite well-documented cognitive impairments in bipolar disorder (BD) and recent reports of altered anatomical network organisation, the association between connectivity and cognitive impairments in BD remains unclear. Methods: We examined the role of anatomical network connectivity derived from T1and diffusion-weighted magnetic resonance imaging in impaired cognitive performance in individuals with BD (n=32) compared to healthy controls (n=38). Fractional anisotropy-and number of streamlines-weighted anatomical brain networks were generated by mapping constrained spherical deconvolutionreconstructed white matter between 86 cortical/subcortical bilateral brain regions delineated in the individual's own coordinate space. Intelligence and executive function were investigated as distributed functions using measures of global, rich-club and interhemispheric connectivity while memory and social cognition were examined in relation to subnetwork connectivity. Results: Lower executive functioning related to higher global clustering coefficient in bipolar participants, and lower IQ performance may present with a differential relationship between global and interhemispheric efficiency in BD relative to controls. Spatial recognition memory accuracy and response times were similar between diagnostic groups and associated with basal ganglia and thalamus interconnectivity and connectivity within extended anatomical subnetworks in all participants. No anatomical subnetworks related to episodic memory, short-term memory or social cognition generally or differently in BD. Conclusions: Results demonstrate selective influence of subnetwork patterns of connectivity in underlying cognitive performance generally and abnormal global topology underlying discrete cognitive impairments in BD.

show abstract

Picture free recall performance linked to the brain's structural connectome

Cited by 4 publications

References 76 publications

Sex‐dependent differences in connectivity patterns are related to episodic memory recall

Sex‐dependent differences in connectivity patterns are related to episodic memory recall

The effect of creative expression program in neurocognitive networks performance measured by task and resting-state functional MRI

Neuroanatomical Dysconnectivity Underlying Cognitive Deficits in Bipolar Disorder

Contact Info

Product

Resources

About