This study presents innovative three-degree-of-freedom piezoelectric actuators. Under the piezoelectric force and dry friction, the piezoelectric actuators not only can move in the Z-axis direction, but also rotate around the Y-axis and Z-axis. The Z-axis displacement can reach 62 mm and the rotation angle around the Y-axis and Z-axis can reach 270° and 360°, respectively. Compared with the literature, this innovative actuator design achieves one-degree-of-freedom translation and two-degree-of-freedom rotation. Equations of motion are derived based on the piezoelectric properties and Newton’s law. Two types of actuators are created in this study. In the first type, the centers of four piezoelectric buzzers are attached to an arm while in the other type each rim of the four piezoelectric buzzers is attached to the arm. Experimental results are compared with theoretical results. According to the experimental results, the present actuator can accomplish a translational velocity of 11 mm s−1, a Y-axis angular velocity of 8.96 rad s−1, a Z-axis angular velocity of 2.63 rad s−1, and a force of 2.49 mN. By using four piezoelectric buzzers, this study creates piezoelectric actuators capable of both translational and rotational motions.