Piezo-electric Middle Ear Implant Hearing Aid Experimental Model In Guinea-pig

Zennaro,; Dumon,; Erre,; Guillaume,; Aran, Oya

doi:10.1109/iembs.1992.589426

Cited by 8 publications

(8 citation statements)

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“…The present study confirms and extends the previous examinations of neurophysiologic responses of RW stimulation that had demonstrated CM, CAP, and ABR responses similar to responses generated with acoustic stimulation (23,25,43). The technology achieving RW stimulation differed in these cases; however, electrocochleographic responses were shown to be at least qualitatively similar.…”

Section: Resultssupporting

confidence: 91%

Prospective Electrophysiologic Findings of Round Window Stimulation in a Model of Experimentally Induced Stapes Fixation

Lupo¹,

Koka²,

Holland³

et al. 2009

Otology &Amp; Neurotology

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Section: Resultssupporting

confidence: 91%

Prospective Electrophysiologic Findings of Round Window Stimulation in a Model of Experimentally Induced Stapes Fixation

Lupo¹,

Koka²,

Holland³

et al. 2009

Otology &Amp; Neurotology

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“…Using an AMEI, Dumon et al [1995] confirmed in an animal study the potential for RW stimulation by comparing measurements of acoustically evoked potentials to those evoked by piezoelectric vibrators implanted in the RW. Others have also confirmed this route of stimulation in animal-model studies of RW stimulation [Spindel et al, 1991[Spindel et al, , 1995Zennaro et al, 1992;Koka et al, 2009] by both electromagnetic and piezoelectric AMEI technologies.…”

Section: Rationale For Rw Stimulation By Ameimentioning

confidence: 73%

Round Window Membrane Implantation with an Active Middle Ear Implant: A Study of the Effects on the Performance of Round Window Exposure and Transducer Tip Diameter in Human Cadaveric Temporal Bones

Tringali

Koka²,

Devèze

et al. 2010

Audiol Neurotol

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Objectives: To assess the importance of 2 variables, transducer tip diameter and resection of the round window (RW) niche, affecting the optimization of the mechanical stimulation of the RW membrane with an active middle ear implant (AMEI). Materials and Methods: Ten temporal bones were prepared with combined atticotomy and facial recess approach to expose the RW. An AMEI stimulated the RW with 2 ball tip diameters (0.5 and 1.0 mm) before and after the resection of the bony rim of the RW niche. The RW drive performance, assessed by stapes velocities using laser Doppler velocimetry, was analyzed in 3 frequency ranges: low (0.25–1 kHz), medium (1–3 kHz) and high (3–8 kHz). Results: Driving the RW produced mean peak stapes velocities (H_EV) of 0.305 and 0.255 mm/s/V at 3.03 kHz, respectively, for the 1- and 0.5-mm tips, with the RW niche intact. Niche drilling increased the H_EV to 0.73 and 0.832 mm/s/V for the 1- and 0.5-mm tips, respectively. The tip diameter produced no difference in output at low and medium frequencies; however, the 0.5-mm tip was 5 and 6 dB better than the 1-mm tip at high frequencies before and after niche drilling, respectively. Drilling the niche significantly improved the output by 4 dB at high frequencies for the 1-mm tip, and by 6 and 10 dB in the medium- and high-frequency ranges for the 0.5-mm tip. Conclusion: The AMEI was able to successfully drive the RW membrane in cadaveric temporal bones using a classical facial recess approach. Stimulation of the RW membrane with an AMEI without drilling the niche is sufficient for successful hearing outputs. However, the resection of the bony rim of the RW niche significantly improved the RW stimulation at medium and higher frequencies. Drilling the niche enhances the exposure of the RW membrane and facilitates positioning the implant tip.

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“…Using an AMEP, Dumont et al (1995) have confirmed in an animal study the potential for RW stimulation by comparing measurements of acoustically evoked potentials to those evoked by piezoelectric vibrators implanted on the RW. Others have also confirmed this route of stimulation in animal-model studies of RW stimulation (Spindel et al, 1991(Spindel et al, , 1995Zennaro et al, 1992) by both electromagnetic and piezoelectric AMEP technologies. Although each of these studies demonstrated central auditory system-evoked electrical activity (e.g., auditory brainstem response) could be elicited by RW stimulation, none of them examined in detail the electrocochleographic responses to RW stimulation or tested any specific hypotheses.…”

Section: Introductionmentioning

confidence: 72%

“…For example, Wever et al (1948), in one of the classical studies of RW stimulation, directed sounds to the RW and OW and found similar sound intensities were required to produce constant 10-lV CM amplitude in the cat. Appropriate piezoelectric mechanical stimulation of the RW was shown by Zennaro et al (1992) to produce similar compound action potential responses in the guinea pig as compared to acoustic stimulation. Measurements, however, were limited to stimulus frequencies <2 kHz.…”

Section: Implications For Rw Stimulation With Ameps For Hearing Restomentioning

confidence: 91%

Electrocochleographic and mechanical assessment of round window stimulation with an active middle ear prosthesis

et al. 2010

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Piezo-electric Middle Ear Implant Hearing Aid Experimental Model In Guinea-pig

Cited by 8 publications

References 0 publications

Prospective Electrophysiologic Findings of Round Window Stimulation in a Model of Experimentally Induced Stapes Fixation

Prospective Electrophysiologic Findings of Round Window Stimulation in a Model of Experimentally Induced Stapes Fixation

Round Window Membrane Implantation with an Active Middle Ear Implant: A Study of the Effects on the Performance of Round Window Exposure and Transducer Tip Diameter in Human Cadaveric Temporal Bones

Electrocochleographic and mechanical assessment of round window stimulation with an active middle ear prosthesis

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