Piezoelectric aptasensor with gold nanoparticle amplification for the label-free detection of okadaic acid

Tian, Yulan; Zhu, Ping; Chen, Yating; Bai, Xiaoyu; Du, Liping; Chen, Wei; Wu, Chunsheng; Wang, Ping

doi:10.1016/j.snb.2021.130446

Cited by 38 publications

(20 citation statements)

References 39 publications

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“…1 In another work, gold nanoparticles were used to amplify the OA detection signals based on a piezoelectric aptasensor; this strategy yielded to a LOD of 2.5 × 10 −1 ng mL −1 . 17 It is important to highlight that in comparison to other techniques, the superiority of the proposed sensor resides in its simplicity, ease of use, and the fact that neither labeling nor amplification are necessary. In addition to that, the sensor exhibited excellent stability over an extended period of time during the assay runs.…”

Section: Resultsmentioning

confidence: 99%

Highly sensitive solid-state nanopore aptasensor based on target-induced strand displacement for okadaic acid detection from shellfish samples

Elaguech,

Yin,

Wang

et al. 2023

Sens. Diagn.

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Section: Resultsmentioning

confidence: 99%

Highly sensitive solid-state nanopore aptasensor based on target-induced strand displacement for okadaic acid detection from shellfish samples

Elaguech,

Yin,

Wang

et al. 2023

Sens. Diagn.

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“…pressure, which can be transformed into electrical signals by piezoelectric materials [167][168][169][170] . Wang et al [171] reported a method of detection for okadaic acid using piezoelectric materials by E-AB sensor. After the piezoelectric materials are modified with complementary chains of aptamers, they are incubated together with the mixture of okadaic acid and okadaic acid aptamers.…”

Section: Reviewmentioning

confidence: 99%

Recent Progress on Highly Selective and Sensitive Electrochemical Aptamer-based Sensors

Tang

Liu

Jiang

2022

Chem. Res. Chin. Univ.

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ighly selective, sensitive, and stable biosensors are essential for the molecular level understanding of many physiological activities and diseases. Electrochemical aptamer-based (E-AB) sensor is an appealing platform for measurement in biological system, attributing to the combined advantages of high selectivity of the aptamer and high sensitivity of electrochemical analysis. This review summarizes the latest development of E-AB sensors, focuses on the modification strategies used in the fabrication of sensors and the sensing strategies for analytes of different sizes in biological system, and then looks forward to the challenges and prospects of the future development of electrochemical aptamerbased sensors.

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“…Biosensors are also compact and miniaturized devices that facilitate the advancement of portable sensing systems to monitor on-site effluents [ 29 ]. Bearing in mind the wide range of bio-recognition elements (including enzymatic, immunochemical, non-enzymatic receptor, whole-cell and DNA elements, and molecularly imprinted polymer (MIP)), the various types of biosensors can be classified as (i) electrochemical [ 30 ], (iii) piezoelectric [ 31 ], (ii) optical [ 32 ], and (iv) thermal biosensors [ 33 ] based on their working principles and transducing mechanisms [ 34 ], but the current review paper will cover the topics which are related to electrochemical biosensing. An electrochemical biosensor is based on the interactions between the immobilized bio-recognition element on its surface with binding molecules (the analyte of interest) and generating the changes in electrochemical properties, further translating into a meaningful electrical signal.…”

Section: Introductionmentioning

confidence: 99%

Recent Advancements in Electrochemical Biosensors for Monitoring the Water Quality

et al. 2022

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The release of chemicals and microorganisms from various sources, such as industry, agriculture, animal farming, wastewater treatment plants, and flooding, into water systems have caused water pollution in several parts of our world, endangering aquatic ecosystems and individual health. World Health Organization (WHO) has introduced strict standards for the maximum concentration limits for nutrients and chemicals in drinking water, surface water, and groundwater. It is crucial to have rapid, sensitive, and reliable analytical detection systems to monitor the pollution level regularly and meet the standard limit. Electrochemical biosensors are advantageous analytical devices or tools that convert a bio-signal by biorecognition elements into a significant electrical response. Thanks to the micro/nano fabrication techniques, electrochemical biosensors for sensitive, continuous, and real-time detection have attracted increasing attention among researchers and users worldwide. These devices take advantage of easy operation, portability, and rapid response. They can also be miniaturized, have a long-life span and a quick response time, and possess high sensitivity and selectivity and can be considered as portable biosensing assays. They are of special importance due to their great advantages such as affordability, simplicity, portability, and ability to detect at on-site. This review paper is concerned with the basic concepts of electrochemical biosensors and their applications in various water quality monitoring, such as inorganic chemicals, nutrients, microorganisms’ pollution, and organic pollutants, especially for developing real-time/online detection systems. The basic concepts of electrochemical biosensors, different surface modification techniques, bio-recognition elements (BRE), detection methods, and specific real-time water quality monitoring applications are reviewed thoroughly in this article.

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Piezoelectric aptasensor with gold nanoparticle amplification for the label-free detection of okadaic acid

Cited by 38 publications

References 39 publications

Highly sensitive solid-state nanopore aptasensor based on target-induced strand displacement for okadaic acid detection from shellfish samples

Highly sensitive solid-state nanopore aptasensor based on target-induced strand displacement for okadaic acid detection from shellfish samples

Recent Progress on Highly Selective and Sensitive Electrochemical Aptamer-based Sensors

Recent Advancements in Electrochemical Biosensors for Monitoring the Water Quality

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