Pigment Gallstones and Secondary Calcification of Gallstones

Soloway, Roger D.; Wu, Jin; Xu, Dao-Zhen

doi:10.1007/978-3-642-74619-2_4

Cited by 7 publications

(3 citation statements)

References 21 publications

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“…In diesem Zeitraum hatte sich die Ernährung in Japan dem westlichen Niveau angeglichen. In den ländlichen Gebieten Chinas blieben die braunen Pigmentsteine die weitaus häu-figste Steinart der Gallengänge (90%) [10]. Eine genetische Prädisposition ist wenig wahrscheinlich, da Asiaten nach Auswanderung in Länder der westlichen Welt dieselben Steinarten entwickeln wie die dortige Bevölkerung, obwohl bei deren Eltern noch vermehrt braune Steine nachgewiesen wurden.…”

Section: Risikofaktoren Für Die Entstehung Von Gallengangsteinenunclassified

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Pathogenese der Choledocholithiasis

Neubrand¹,

Sauerbruch²

2001

Visc Med

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Pathogenesis of Choledocholithiasis Bile duct stones may develop primarily within the bile ducts or migrate secondarily from the gallbladder into the common bile duct. According to their site of formation, their compositions differ from each other. In this article we describe the chemical characteristics of both stone types and discuss risk factors and pathogenesis of the stones formed in the bile ducts.

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Section: Risikofaktoren Für Die Entstehung Von Gallengangsteinenunclassified

“…In der asiatischen Bevölkerung sind primäre Gallengangsteine sehr viel häufiger. In Japan entstehen 30% der Gallengangsteine primär im Ductus choledochus [9], in ländlichen Gebieten Chinas sind es sogar 90% [10].…”

Section: Introductionunclassified

Pathogenese der Choledocholithiasis

Neubrand¹,

Sauerbruch²

2001

Visc Med

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“…Cholate is one of two major Although much research on cholelithiasis has bile salts synthesized by the liver and accounts been undertaken, 1,2 the mechanisms of gallstone for about 30% of bile salts in bile. We found that formation are still unclear, and some features are the bile salt-metal complex precipitates formed not explained.…”

Section: Introductionmentioning

confidence: 99%

Periodic and chaotic precipitation phenomena in bile salt system related to gallstone formation

Peng¹,

Wu²,

Soloway³

et al. 1997

Biospectroscopy

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Copper bilirubinate and black pigment gallstone

Shen

Soloway

et al. 1995

Biospectroscopy

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A series of copper bilirubinate complexes (CuBR) was synthesized in solution and in solid state to mimic the black color of the black‐pigment gallstone and to explore the formation mechanism of the gallstonein vitro. The variation of the copper contents of these samples indicated that CuBR also exhibits nonstoichiometric characteristics from the FTIR study, i.e., both the so‐called acid and neutral copper complex moieties exist in CuBR. The NH groups in pyrrole and lactam groups of bilirubin (H2BR) are binding to the copper ions. An EPR study demonstrates the generation of free radicals and the variation of its electronic structure and conjugation system in the skeleton of H2BR molecule during complex formation. A polymer of CuBR may form through the reaction of H2BR with copper ions. © 1995 John Wiley & Sons, Inc.

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Pigment Gallstones and Secondary Calcification of Gallstones

Cited by 7 publications

References 21 publications

Pathogenese der Choledocholithiasis

Pathogenese der Choledocholithiasis

Periodic and chaotic precipitation phenomena in bile salt system related to gallstone formation

Copper bilirubinate and black pigment gallstone

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