Pigmentary mosaicism with left hemihypertrophy and syndactyly: Case report with review of literature

Abstract

Pigmentary mosaicism is a spectrum of disorders characterized by dyspigmentation along the lines of blaschko and other patterns such as phylloid, checkerboard and patchy pigmentation without midline separation. This group of disorders may be associated with or without systemic abnormalities. Pigmentary mosaicism includes hypomelanoses of Ito, linear and whorled nevoid hypermelanosis, phylloid hypo-and hypermelanosis and pigmentary mosaicism of both hypopigmented and hyperpigmented type. We describe a case of pigmentary mosaicism with constellation of multiple extracutaneous abnormalities.

Unilateral Syndactyly, Hemihypertrophy, and Hyperpigmentation with Mosaic 2q35 Deletion

“…[ 17 ] The present case and the one reported by Sriniwas et al . [ 17 ] showed extra-cutaneous manifestation of asymmetry of limbs and nonosseous syndactyly of third and fourth fingers of the right hand. Extracutaneous manifestations are common in PM.…”