Pilot evaluation of an optimized context-specific drug–drug interaction alerting system: A controlled pre-post study

Evaluation of an intravenous preparation information system for improving the reconstitution and dilution process

“…After implementing the new system, it is critical for users or providers to monitor the impact of the system and if necessary, improve the alert contents [43,[45][46][47]. This study confirmed that system optimization would be required and can be achieved by monitoring the impact of alerts or information provision in medical institutions.…”

Optimizing Drug-Drug Interaction Alerts Using a Multidimensional Approach

“…3, 4,7,9,10,14,21,22 Previous research has reported effective techniques for categorizing historical interruptive DDI alert data for critical review, organizing at the drug or drug category level, and calculating frequencies of alert occurrence. [11][12][13][14][15][16] Interdisciplinary panels can review an institution's alert data and safely identify alerts to deactivate or modify. 7,8 Using a validated survey provided broad clinician insights and helped fulfill previous recommendations to use multiple sources of information to evaluate interruptive alert quality.…”

“…reported, classifying DDI alerts by drug class increased the efficiency of our efforts and identified more DDI alerts for refinement than in our previous efforts to analyze metrics for individual DDI alerts, and it identified that only 25 alert groups were responsible for 46% of alert firings. [11][12][13][14][15][16]21 Refinement of these alert groups resulted in a significant decrease in the frequency of DDI alerts across multiple clinician roles (Fig 2). Importantly, our experience was consistent with previous efforts showing that refining a relatively small number of drug-drug and drug-class alerts can encompass a large percentage of all occurring DDI alerts.…”

“…9,10 Recently, a drug-drug interaction (DDI) CDS workgroup recommended combining clinician feedback and perceptions of alert systems with current alert metrics to target alerts for deactivation and tracking the performance of alert system improvements. 7 One mechanism for alert system improvements is the guided review of an interdisciplinary clinician panel, [11][12][13][14][15][16] which can evaluate DDI alert frequencies both individually 11,15 and by drug class. [12][13][14] Organizing DDI alerts into drug-class and class-class categories allows for a large number of individual DDI alerts to be evaluated for clinical effectiveness.…”

Hospital Pharmacy in Belgium: From Moving Boxes to Providing Optimal Therapy

“…29 Key to this evolution has been the introduction of clinical pharmacy services. [30][31][32][33][34][35] In the year 2000, some universities and university hospitals started small clinical pharmacy projects, and the first hospital pharmacists started to appear on the wards, building up their experience with individual patients, in collaboration with physicians and nurses. In the years that followed, clinical pharmacy courses were started in the universities, with the development of clinical pharmacy services leading to the establishment of a "network of pharmacy and therapeutics committees" by the government in 2004.…”