Pilyriasis rubry pilaris and human immunodeficiency virus infection-type 6 pityriasis rubra pilaris?

Miséry, Laurent; Faure, M; Claudy, A

doi:10.1046/j.1365-2133.1996.d01-1114.x

Cited by 35 publications

(30 citation statements)

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“…PRP is a rare papulosquamous disorder of unknown aetiology. It has been associated with impaired cell‐mediated immunity, and familial variants have been linked to genetic mutations relevant to other autoinflammatory skin disorders . Clinical findings include orange/red plaques with follicular hyperkeratosis and characteristic ‘islands of sparing’, palmoplantar hyperkeratosis, and frequent progression to erythroderma with pityriasiform scale…”

Section: Discussionmentioning

confidence: 99%

Pityriasis rubra pilaris-like erythroderma secondary to phosphoinositide 3-kinase inhibition

et al. 2018

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Section: Discussionmentioning

confidence: 99%

Pityriasis rubra pilaris-like erythroderma secondary to phosphoinositide 3-kinase inhibition

et al. 2018

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“…Although other entities, such as pityriasis rubra pilaris, lichen spinulosus and HIV-associated occlusion follicular syndrome, have been linked to HIV infection [2,3,4,5,6,7,8], we have not observed any such case, so we consider them rare diseases. There are many diseases that can present as itchy folliculitis in HIV-infected patients and are related to immunosuppression and/or immunorestoration [19].…”

Section: Discussionmentioning

confidence: 71%

“…Several dermatoses with follicular occlusion have been described in HIV-infected patients, including acne vulgaris, drug-induced acneiform eruptions, a special form of pityriasis rubra pilaris, lichen spinulosus and acne inversa (hidradenitis suppurativa) [1,2,3,4,5]. These entities appear isolated or associated with each other in an independent disease named ‘HIV-associated follicular syndrome’ [6,7,8].…”

Section: Introductionmentioning

confidence: 99%

Acne Is Not a Stigma of HIV Infection: A Review of 36 Patients

Almagro¹,

Pozo²,

García-Silva³

et al. 2005

Dermatology

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Introduction: Several diseases with follicular occlusion have been described in HIV-infected patients and can appear isolated or associated with each other in an independent disease named ‘HIV-associated follicular syndrome’. Worsening of cutaneous lesions during the course of infection in patients with previous acne vulgaris, late onset or severe forms of acne have been reported in HIV-infected patients. Patients and Methods: A prospective study of 335 HIV-infected patients was performed in our hospital. A meticulous dermatological exploration in all patients was made, and multiple data were stored into a Microsoft Access 97 program. Patients diagnosed as having acne were considered separately, and we studied their characteristics. A statistical analysis with SPSS 9.0 (Statistical Package for the Social Sciences) was performed. Results: Thirty-six patients (10.8%) were diagnosed as having acne. Papulopustular lesions were the most frequent clinical presentation. Most lesions were localized on the face or on the back, and 80% of patients had mild to moderate acne; 40% of them required no treatment and the remainder was treated with topical measures, oral antibiotics and isotretinoin. 85% of cases reported the onset of acne during adolescence or before HIV infection and without any relationship with this disease. No relation between acne intensity and stage of HIV infection was observed. A multivariate analysis showed that the most important variable was age. Discussion: In contrast to previous reports, no greater intensity or modifications in acne lesions were observed in our HIV-infected patients during the course of the disease. In the majority of cases, cutaneous lesions started before HIV infection, during adolescence, and the most important factor for suffering from acne was young age. In contrast to data reported in the literature, no relation of acne lesions to CD4 lymphocyte count or AIDS case criteria was found in our patients. Conclusions: Acne in HIV-infected patients has characteristics similar to those in non-HIV-infected patients. The age is the most important factor for the appearance of lesions that usually develop during adolescence. Acne lesions are not modified by HIV infection, and no relationship with the severity of HIV infection has been observed.

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“…In recent years, a type VI PRP associated with HIV infection, characterized by a distinctive triad of nodulocystic acne, lichen spinulosus, and a PRPlike eruption, has been proposed. 6,7 Because of the rarity of the disease, especially in children, large-scale studies of juvenile PRP are limited with diverse conclusions about its manifestation, classification, and treatment. 4,8 Here we report a long-term observational study of 28 juvenile cases in Taiwan.…”

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confidence: 99%