Pityriasis Rubra Pilaris

Davidson, Chester L.

doi:10.1001/archderm.1969.01610260051008

Cited by 38 publications

(3 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Hyperkeratosis, an increased number of granular layers and eczematous acanthosis were constant features. On the other hand, basal cell vacuolization [4,18] was not seen in any case and arrector muscle hyperplasia and epithelial tendon on the follicle [12] was not seen often enough to be of diagnostic help.…”

Section: Discussionmentioning

confidence: 89%

“…Davidson et al [4] had 2 cases of familial PRP in their series and others [8,16] have described single cases. K int el al.…”

Section: Discussionmentioning

confidence: 96%

“…Only 9 of 28 patients with a proper follow-up time had been cured completely, in contrast to the series of Davidson el al. [4], 5 of these began with a short outburst of erythroderma. The children had the same prognosis as the adults, which confirms the statements of other authors [4], The striking red color of the skin as a sign of an acute inflammation as well as the occasional association of PRP and muscle and joint involvement [1] warranted the autoimmune and immunofluorescent studies which had not to our knowledge been made so far in a qualified series.…”

Section: Discussionmentioning

confidence: 99%

See 2 more Smart Citations

Pityriasis rubra pilaris

et al. 1976

View full text Add to dashboard Cite

In a clinical study, 27 of 31 cases of pityriasis rubra pilaris (PRP) had two or more of the following clinical features: erythroderma, well-confined healthy islands inside the inflammatory areas, keratoderma of the palms and soles, or visible follicular hyperkeratosis. Histological features were: perifollicular parakeratosis in 26 cases, hyper-keratosis in 27 cases; the number of granular layers varied greatly from case to case and within one specimen; acanthosis was eczematous in 20 cases and psoriasiform in 8 cases. Erythroderma in PRP in this study was self-healing, lasting 2–6 months with one exception, but PRP must as a whole be considered a mild, chronic disease lasting on average 5.7 years. Complete recovery occurred in only 8 patients and 5 of these had had an erythro-dermic onset. Serum vitamin A level and tolerance test were normal. No immunological aberrations could be found. The HLA phenotype frequencies in PRP patients did not differ significantly from those in a Finnish control population. The autoradiographic study of the epidermal cells showed an increase in the cell production in the epidermis.

show abstract

Section: Discussionmentioning

confidence: 89%

“…Davidson et al [4] had 2 cases of familial PRP in their series and others [8,16] have described single cases. K int el al.…”

Section: Discussionmentioning

confidence: 96%