PLA/chitosan/keratin composites for biomedical applications

Chitin and chitosan from Brazilian Atlantic Coast: Isolation, characterization and antibacterial activity

“…It is used in food preservation [30], cosmetics [31,32], agriculture [33], biotechnology [34], textiles [1,17,[35][36][37] as well as medical fields [38][39][40]. Shrimp shell wastes contain about 20-30% chitin which can be isolated to produce many products such as chitosan, glucosamine and their derivatives, but since chitin is closely associated with proteins, minerals, and pigments, all these components have to be removed to reach to the highest purity necessary for bio-medical applications [41][42][43][44][45][46][47][48][49][50][51][52][53]. The medical applications of chitin and chitosan were limited due to the allergic properties [54,55] of the both biopolymers, the phenomenon due to the presence of some impurities like proteins, pigments, and heavy metals attached into the chitin/chitosan chains.…”

Preparation, Characterization and Evaluation of Antifungal Efficacy of Chitosan/Soy Phosphatidylcholine Topical Films Containing Griseofulvin

“…Due to the hydrophilic nature of chitosan, films composed of chitosan alone showed lack of stability, chemical cross linking with agents such as glutaraldehyde could overcome this, but they have been found to be toxic and the films are often non-biodegradable (3). Blending chitosan with other materials to produce stable films by physical cross-linking achieved via electrostatic and/or hydrogen bonding interaction has been investigated widely (3)(4)(5)(6)(7)(8)(9)(10).…”

Obtención de una película a base de almidón hidroxipropilado producida por extrusión soplado

“…Las mezclas del PLA y almidón han sido producidas con el objetivo de mantener propiedades físicas adecuadas en los poliésteres sintéticos biodegradables reduciendo su costo [12,13,14]. Sin embargo, la mezcla anterior tiene un limitante basado en, una baja elongación en el punto de rotura, similar a la presentada por el PLA puro (3,1 a 5,8%) [14,15]. Para contribuir en el aumento de flexibilidad, Sarazin et al, (2008), incorporaron policaprolactona (PCL) en la mezcla binaria de PLA y almidón, reportando la consecución de valores de elongación en el punto de rotura del orden del 55% [16].…”