Plain articaine or prilocaine for spinal anaesthesia in day-case knee arthroscopy: a double-blind randomized trial

Hendriks, Mathijs P.; Weert, C.J.M. de; Snoeck, M.M.J.; Hu, Hong-Tao; Pluim, M. A. L.; Gielen, M.J.M.

doi:10.1093/bja/aen357

Cited by 41 publications

(27 citation statements)

References 12 publications

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“…45 Nevertheless, these findings were not confirmed by other studies. 44 No transient neurological symptoms occurred in either group, which is in accordance with current literature, 27,33,39,46 suggesting that both local anesthetics are safe for same-day spinal anesthesia. The low mean (SD)VAS at discharge [9 (2) for prilocaine; 5 (1) for ropivacaine] associated with high patient satisfaction and uneventful follow-up showed that both hyperbaric 2% prilocaine and 0.4% plain ropivacaine were equally safe for short-lasting same-day spinal anesthesia.…”

Section: Discussionsupporting

confidence: 88%

Intrathecal hyperbaric 2% prilocaine versus 0.4% plain ropivacaine for same-day arthroscopic knee surgery: a prospective randomized double-blind controlled study

Aguirre

Borgeat

Bühler

et al. 2015

Can J Anesth/J Can Anesth

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Intrathecal hyperbaric 2% prilocaine versus 0.4% plain ropivacaine for same-day arthroscopic knee surgery: a prospective randomized double-blind controlled study Prilocaïne 2 % hyperbare versus ropivacaïne 0,4 % en injection intrathécale pour une arthroscopie du genou en chirurgie ambulatoire: une étude randomisée contrôlée prospective à double insu AbstractBackground Short-duration spinal anesthesia is a good option for ambulatory knee surgery. Hyperbaric 2% prilocaine has short onset and rapid recovery times and, therefore, may be well suited in this setting. The aim of this study was to compare the times to reach motor block, motor block resolution, and discharge from the postanesthesia care unit (PACU) between hyperbaric 2% prilocaine and 0.4% plain ropivacaine.Methods In this prospective randomized double-blind study, 140 patients (ages 18-80 yr and American Society of Anesthesiologists physical status I-II) scheduled for elective unilateral arthroscopic knee surgery lasting \ 45 min were allocated to either 3 mL of 2% prilocaine (60 mg) or 3 mL of 0.4% plain ropivacaine (12 mg). Time to reach complete recovery of motor block, time to reach criteria for discharge, as well as side effects up to 48 hr after discharge were recorded. Results The median (interquartile range [IQR]) time to recovery from the motor block was faster in the 2% prilocaine group compared with the 0.4% ropivacaine group (180 [169-240] min vs 240 [180-300] min, respectively; median difference, 60 min, 95% confidence interval (CI), 23 to 97 min; P = 0.036). The median [IQR] time to reach discharge criteria was similar between the two groups (330 min vs, 335 [290-395] min; median difference 5 min, 95% CI, -25 to 35 min; P = 0.330). The incidence of side effects was low and similar in both groups. No case of transient neurologic symptoms occurred in either group. Conclusion The recovery of motor block was faster after intrathecal administration of hyperbaric 2% prilocaine compared with 0.4% plain ropivacaine; however, discharge time was similar between the two groups. Both drugs showed a similar risk profile. RésuméContexte La rachianesthésie de courte durée est une bonne option lorsqu'on pratique une chirurgie ambulatoire du genou. Le délai d'action de la prilocaïne 2 % hyperbare est court et son temps de récupération rapide; cet agent

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Section: Discussionsupporting

confidence: 88%

Intrathecal hyperbaric 2% prilocaine versus 0.4% plain ropivacaine for same-day arthroscopic knee surgery: a prospective randomized double-blind controlled study

Aguirre

Borgeat

Bühler

et al. 2015

Can J Anesth/J Can Anesth

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“…[11][12][13][14][15][16][17][18][19][20][21][22][23][24][25][26] In 41 studies (5,548 patients), urinary retention or PVR with intrathecal anesthesia was assessed (Table 3), 11,13,16,17,20,22, and in 39 studies (4,938 patients), urinary retention or PVR with epidural anesthesia and/or analgesia was assessed (Table 4). 28,33,35,43,[48][49][50]54, An additional five studies involved both intrathecal and epidural techniques.…”

Section: Resultsmentioning

confidence: 99%

Neuraxial anesthesia and bladder dysfunction in the perioperative period: a systematic review

Choi

Mahon

Awad

2012

Can J Anesth/J Can Anesth

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Purpose Urinary retention requiring catheterization carries the risk of infection. Neuraxial anesthesia causes transient impairment of bladder function ranging from delayed initiation of micturition to frank urinary retention. We undertook a review of the literature to determine the elements of neuraxial anesthesia and analgesia that prolong bladder dysfunction and increase the incidence of urinary retention. Methods We performed a systematic search of the PubMed, MEDLINE, and EMBASE databases (from January 1980 to January 2011) to identify studies where neuraxial anesthesia and/or analgesia were employed and at least one of the following outcomes was reported: urinary retention, time to micturition, or post void residual. We included randomized controlled trials and observational studies published in the English language and we excluded case reports. The randomized trials were graded according to the Jadad score. Principal findings Our search yielded 94 studies, and in 16 of these studies, the authors reported time to micturition after intrathecal anesthesia of varying local anesthetics and doses. Intrathecal injections were performed in 41 of these studies, epidural anesthesia/analgesia was used in 39 studies, and five studies involved both the intrathecal and epidural routes. Meta-analysis was not possible because of the heterogeneity of interventions and reported outcomes. The duration of detrusor dysfunction after intrathecal anesthesia is correlated with local anesthetic dose and potency. The incidence of urinary retention displays a similar trend and is further increased by the presence of neuraxial opioids, particularly long-acting variants. Urinary tract infection secondary to catheterization occurred rarely. Conclusions Neuraxial anesthesia/analgesia results in transient detrusor dysfunction. The duration of dysfunction depends on the potency and dose of medication used; however, it does not appear to result in significant morbidity.

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“…Two studies investigated urinary retention rates in patients receiving 50 mg and 60 mg hyperbaric prilocaine and found rates of 8.3% and 25% [24,25]. It seems that low dose SPA as used in our study does not cause urinary retention, especially when prilocaine is used.…”

Section: Prilocaine (N=80)mentioning

confidence: 50%

Spinal hyperbaric prilocaine vs. mepivacaine in perianal outpatient surgery

Gebhardt

Beilstein

Herold³

et al. 2014

Open Medicine

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Plain articaine or prilocaine for spinal anaesthesia in day-case knee arthroscopy: a double-blind randomized trial

Abstract: Spinal anaesthesia with plain articaine 50 mg resulted in a faster recovery of motor function and earlier spontaneous voiding compared with plain prilocaine 50 mg. Surgical anaesthesia was not different. The incidence of TNS was low.

Cited by 41 publications

References 12 publications

Intrathecal hyperbaric 2% prilocaine versus 0.4% plain ropivacaine for same-day arthroscopic knee surgery: a prospective randomized double-blind controlled study

Intrathecal hyperbaric 2% prilocaine versus 0.4% plain ropivacaine for same-day arthroscopic knee surgery: a prospective randomized double-blind controlled study

Neuraxial anesthesia and bladder dysfunction in the perioperative period: a systematic review

Spinal hyperbaric prilocaine vs. mepivacaine in perianal outpatient surgery

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