Planning and delivery of intensity‐modulated radiation therapy

Yu, C; Amies, Christopher; Svatos, M

doi:10.1118/1.3002305

Cited by 61 publications

(33 citation statements)

References 160 publications

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“…The remaining 86 patients received RT using five-field Intensity Modulated RadioTherapy (IMRT) configuration. 18 Eighty-nine patients received a total dose of 74 Gy in 37…”

Section: Radiotherapymentioning

confidence: 99%

Pilot study on virtual imaging for patient information on radiotherapy planning and delivery

et al. 2015

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a b s t r a c tIt is widely accepted that health professionals might sometimes underestimate cancer patients' needs for information on the complex process of radiotherapy (RT) planning and delivery. Furthermore, relatives might also feel excluded from the treatment of their loved ones. This pilot study was carried out in order to assess whether both patients and their relatives would welcome further information on RT planning and delivery using the virtual reality (VR) system VERT. One hundred and fifty patients with different types of cancer receiving radical RT were included in the study. Patients and relatives were shown using VERT on a one-to-one basis with an oncologist or a radiographer, a standard room where RT is given, a linear accelerator, and how RT is planned and delivered using their own planning CT Scans. Patients welcomed this information as it helped them to reduce their fears about RT. Relatives felt also more involved in the treatment of their loved one. The results obtained in this pilot study show that VR aids could become an important tool for delivering information on RT to both patients and relatives.© 2015 The College of Radiographers. Published by Elsevier Ltd. All rights reserved. IntroductionThere is clear evidence suggesting there is often a gap between the information provided to patients regarding their disease and management, and the amount of information patients wish to receive.1 Furthermore, it is not uncommon for clinicians to underestimate cancer patients' needs for information, 2 especially when the vast majority of cancer patients want to be thoroughly informed about their illness. 3 Despite this, there are still problems with respect to the provision of information which could satisfy most patients. 4 The importance of the provision of information to patients has been stressed by the Department of Health 5 stating that is a key requirement in current cancer services standards in the UK. However, it cannot be assumed that all patients want substantial information regarding their treatment as some might prefer to fully trust their doctor rather than being involved in taking any decisions that could affect their management. While several studies have addressed these issues, 6,7 further work is still required to improve the understanding of patients' needs. Furthermore, relatives might feel sometimes disengaged in the management of their loved ones and might consider themselves being excluded from several areas within the management process. The negative psychological impact upon partners and other relatives of cancer patients is well documented, 8 and such negative effect is (amongst many other factors) widely associated with lack of medical information given to them. It has long been argued that providing tailored information to relatives as well as patients in general cancer care is a positive aspect of the treatment process 9 and there is little doubt that such inclusionary practice should be encouraged in cancer care.A clear example where provision of information to patien...

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“…The remaining 86 patients received RT using five-field Intensity Modulated RadioTherapy (IMRT) configuration. 18 Eighty-nine patients received a total dose of 74 Gy in 37…”

Section: Radiotherapymentioning

confidence: 99%

Pilot study on virtual imaging for patient information on radiotherapy planning and delivery

et al. 2015

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“…A computer performs a three-dimensional (3D) transformation of the Ct slices and creates a digitally reconstructed radiograph (Drr). the beams are very precisely directed and the nearby normal tissue receives less doses (82). Intensity modulated radiation therapy (IMrt) is an advanced type of conformal radiation.…”

Section: Radiation Delivery Methodsmentioning

confidence: 99%

Radiotherapy and wound healing: Principles, management and prospects (Review)

Gieringer

Gosepath²,

Naim³

2011

Oncol Rep

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Abstract. radiation therapy is a major therapeutic modality in the management of cancer patients. Over 60% of these patients receive radiotherapy at some point during their course of treatment and over 90% will develop skin reactions after therapy. problematic wound healing in radiation-damaged tissue constitutes a major surgical difficulty and despite all efforts, irradiated skin remains a therapeutic challenge. this review provides an overview of the fundamental principles of radiation therapy with regards to the wound healing in normal and irradiated skin. Furthermore, it presents techniques that describe how to prevent and manage skin side effects as well as prospects that may improve cutaneous wound repair in general and in irradiated skin.

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“…Evidently, any room for improving an IMRT plan depends strongly on the degrees of freedom provided by the machines and the related facilities. 2 Multileaf collimator (MLC) is a critical piece of the equipment which makes an effective delivery of intensity modulated beams possible. During the last two decades, MLCs have been continually refined by linear accelerator vendors to accommodate the development of IMRT.…”

Section: Introductionmentioning

confidence: 99%

Improving IMRT‐plan quality with MLC leaf position refinement post plan optimization

et al. 2012

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Purpose: In intensity-modulated radiation therapy (IMRT) planning, reducing the pencil-beam size may lead to a significant improvement in dose conformity, but also increase the time needed for the dose calculation and plan optimization. The authors develop and evaluate a postoptimization refinement (POpR) method, which makes fine adjustments to the multileaf collimator (MLC) leaf positions after plan optimization, enhancing the spatial precision and improving the plan quality without a significant impact on the computational burden. Methods: The authors' POpR method is implemented using a commercial treatment planning system based on direct aperture optimization. After an IMRT plan is optimized using pencil beams with regular pencil-beam step size, a greedy search is conducted by looping through all of the involved MLC leaves to see if moving the MLC leaf in or out by half of a pencil-beam step size will improve the objective function value. The half-sized pencil beams, which are used for updating dose distribution in the greedy search, are derived from the existing full-sized pencil beams without need for further pencil-beam dose calculations. A benchmark phantom case and a head-and-neck (HN) case are studied for testing the authors' POpR method. Results: Using a benchmark phantom and a HN case, the authors have verified that their POpR method can be an efficient technique in the IMRT planning process. Effectiveness of POpR is confirmed by noting significant improvements in objective function values. Dosimetric benefits of POpR are comparable to those of using a finer pencil-beam size from the optimization start, but with far less computation and time. Conclusions: The POpR is a feasible and practical method to significantly improve IMRT-plan quality without compromising the planning efficiency.

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Planning and delivery of intensity‐modulated radiation therapy

Cited by 61 publications

References 160 publications

Pilot study on virtual imaging for patient information on radiotherapy planning and delivery

Pilot study on virtual imaging for patient information on radiotherapy planning and delivery

Radiotherapy and wound healing: Principles, management and prospects (Review)

Improving IMRT‐plan quality with MLC leaf position refinement post plan optimization

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