Plantago ovata husks-supplemented diet ameliorates metabolic alterations in obese Zucker rats through activation of AMP-activated protein kinase. Comparative study with other dietary fibers

Hypolipidemic applications of microcrystalline cellulose composite synthesized from different agricultural residues

“…Thus, this composite has the potential to prevent onset of pathologies associated with hyperlipidemia. Consequently [25], Galisteo et al verified that methylcellulose-starch supplemented diet produced a reduction in circulating lipids concentration and this may be due to the reduction in free fatty acid circulating concentration because of the reduction in tumor necrosis factor (TNF-␣) secretion and the higher production of adiponectin by visceral adipose tissue which reflects the failure in weight gain [62]. Circulating free fatty acids play an important role in stimulating hepatic triglyceride production.…”

“…The improvements in bowel habit demonstrate the benefit of insoluble dietary fibers in the nutrition management of children with malabsorption and short gut syndrome [24]. Additionally, the intake of a diet supplemented with MCC as dietary fibers improves obesity and lipid profile [25]. Alternatively Orlistat is a drug that is used to promote weight loss in persons who are overweight or obese.…”

Does Dietary Fiber Affect the Levels of Nutritional Components after Feed Formulation?

“…The restrictive enzymes in lipogenesis is controlled by the AMP-activated proteins kinase (AMPK). For example, supplementing 5 g of Plantago ovata to the diet of rats increased the phosphorylation of AMPK, and hence, affecting acetyl-CoA carboxylase [96]. Also, supplementing 10 g per 100 g of fructooligosaccharide in rats' diet reduced hepatic acetyl-CoA carboxylase expression [97].…”

Dietary Fiber and Availability of Nutrients: A Case Study on Yoghurt as a Food Model

“…Acetyl-CoA carboxylase is the rate-limiting enzyme in lipogenesis and is regulated by AMP-activated protein kinase (AMPK). In a 10-week study comparing obese and lean rats, adding 5 g of P. ovata to rat chow increased the phosphorylation of AMPK, consequently inhibiting acetyl-CoA carboxylase [50]. Fructooligosaccharide (10g/100g) also has been shown to decrease the hepatic acetyl-CoA carboxylase expression in rats [51].…”