Plantes toxiques à usage médicinal du pourtour méditerranéen

Hammiche, Victoria; Merad, Rachida; Azzouz, Mohamed

doi:10.1007/978-2-8178-0375-3

Cited by 44 publications

(39 citation statements)

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“…37 However, local population easily recognize this species with its large and highly toxic bulbs. 11,28 Its toxicity should be due to alkaloids, as in the case for example, of the Colchicaceae although this is yet to be adequately tested. 13 B. amoena is also diploid with 2n=18 and a chromosome base number of x=9.…”

Section: Resultsmentioning

confidence: 99%

“…Therefore, misidentification as well as inappropriate use, causes numerous cases of life-threatening poisoning. 28 Furthermore, many of the medicinal species are over-exploited and endangered; most of them are not yet taxonomically studied. In this work, we aim to highlight the significance of systematic and karyological data to interpret and to evaluate the infraspecific diversity of plants, particularly those used in traditional pharmacopeia, endemics or isolated populations which can able to produce adapted chemotypes.…”

Section: Introductionmentioning

confidence: 99%

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Cytotaxonomic Diversity of some Medicinal Species of Hyacinthaceae from Algeria

Azizi¹,

Amirouche²,

Amirouche³

2016

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Introduction:The Hyacinthaceae family is a large group of attractive petaloid species which synthesize specialized metabolites involved in their pharmacological usefulness. In Algeria, bulbous plants have long been one of the most trusted sources of traditional medicines. The aim of this work is to highlight the significance of systematic and karyological data to evaluate the diversity of species used in traditional pharmacopeia, particularly those endemics or isolated populations which can produce adapted chemotypes. Materials and Methods: Analyses were performed on natural populations of four endemic and rare Hyacinthaceae, Battandiera amoena, Drimia noctiflora, D. fugax and D. undata sampled in contrasted biogeographic areas of Algeria, in coastal hills and in the Saharan border. Chromosomes number, karyotype formulas and asymmetry indices were established for all taxa. Results: The three species of the genus Drimia were diploid with 2n=2x=20 chromosomes. In Battandiera amoena chromosome number is 2n=2x=18. Karyotype analyses reveal marked variation in length and chromosomes morphology and in the chromosomal asymmetry indices. Conclusion:Cytotaxonomical data are discussed in relation to the endemism and the biogeographical distribution of the species and in the context of the conservation of the biodiversity in Algeria.

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Section: Resultsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Cytotaxonomic Diversity of some Medicinal Species of Hyacinthaceae from Algeria

Azizi¹,

Amirouche²,

Amirouche³

2016

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“…Traditional medicine states its use for antiinflammatory, antibacterial, laxative‐purgative and smooth muscle relaxant properties, that appear to be due to the content in active principles (especially cucurbitacins) . It is known as a toxic species, but despite this fact, recent scientific sources confirm its promising therapeutical potential …”

Section: Introductionmentioning

confidence: 99%

“…[8,10] Traditional medicine states its use for antiinflammatory, antibacterial, laxative-purgative and smooth muscle relaxant properties, [1] that appear to be due to the content in active principles (especially cucurbitacins). [11] It is known as a toxic species, [12] but despite this fact, recent scientific sources confirm its promising therapeutical potential. [1,13] There is little evidence about the content of flavonoids in this species, as most of the studies are focused on its content of cucurbitacins, that seem to be found mainly in roots.…”

Section: Introductionmentioning

confidence: 99%

Flavonoid composition, cellular antioxidant activity and (myelo)peroxidase inhibition of a Bryonia alba L. (Cucurbitaceae) leaves extract

Ielciu

Mouithys‐Mickalad

Franck

et al. 2019

Journal of Pharmacy and Pharmacology

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Objectives The aim of the present study consisted in the isolation of flavonoids from the leaves of Bryonia alba L. and evaluation of their antioxidant activity and inhibition on peroxidase‐catalysed reactions. Methods Flavonoids were isolated by preparative HPLC‐DAD and their structures were elucidated by MS and NMR. Inhibitory effect was tested by the horseradish peroxidase and the myeloperoxidase assays. Cellular antioxidant assays consisted in testing the inhibitory activity on the reactive oxygen species released upon activation of neutrophils freshly isolated ex vivo from equine blood and of human monocytes‐derived macrophages in vitro. Whole organism toxicity was assessed on zebrafish larvae. Key findings Four flavonoids (lutonarin, saponarin, isoorientin and isovitexin) were isolated. The performed assays showed significant antioxidant activity and inhibition for the peroxidase‐catalysed reactions. Absence of cellular and zebrafish toxicity was confirmed. Conclusions Bryonia alba L. leaves are particularly interesting for their flavonoids content and showed significant inhibitory effect on peroxidase‐catalysed oxidation of substrates (Amplex Red and L012), as well as antioxidant/antiradical activity, proving that this species has a medicinal potential. Moreover, the present study highlights the absence of the toxicity of these leaves and offers though a novel perspective on the species, previously known as being toxic.

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“…They are a rich source of different bioactive compounds such as polyphenols [2], flavonoids [3,4], iridoidglycosides [5,6], and globularin [7]. It includes one species in Algeria, Globulariaalypum L. (the globe daisy) which is known locally as Tasselgha [8], or Ain Larneb [9]. This plant, belonging to Globulariaceae family, is a perennial wild shrub and is one of the most traditional plant remedies in the Algerian folk medicine in the treatment of a great number of diseases (hypertension, cardiac disorders, renal colic, and various cancerous lesions of the stomach, urolithiasis, rheumatism, gout, typhoid, intermittent fever and diabetes [10,11], colon, rectum, liver, esophagus, and diabetes [12].…”

Section: Introductionmentioning

confidence: 99%

Chemical Composition and Antioxidant Activity of Globularia Alypum L. Leaves Essential Oil from Ain-Defla (Algeria)

Amri¹,

Hamadouche

Alsafra

et al. 2018

ChChT

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The chemical composition of essential oil obtained by hydro-distillation with 2.10±0.09 % yield from dried Globularia alypum L. leaves was analyzed by GC-MS. It was determined 60 components representing 99.04 % of total oil. For the evaluation of the mentioned antioxidant activity, three different approaches were performed: the 2,2-diphenyl-1-picrylhydrazyl (DPPH) free radical scavenging, β-carotene bleaching (BCB) test systems and ferric reducing/antioxidant power assay (FRAP).The antioxidant was compared with that of synthetic antioxidant ascorbic acid. These findings indicate that the G.alypum essential oil exhibited good antioxidant properties.

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Plantes toxiques à usage médicinal du pourtour méditerranéen

Cited by 44 publications

References 0 publications

Cytotaxonomic Diversity of some Medicinal Species of Hyacinthaceae from Algeria

Cytotaxonomic Diversity of some Medicinal Species of Hyacinthaceae from Algeria

Flavonoid composition, cellular antioxidant activity and (myelo)peroxidase inhibition of a Bryonia alba L. (Cucurbitaceae) leaves extract

Chemical Composition and Antioxidant Activity of Globularia Alypum L. Leaves Essential Oil from Ain-Defla (Algeria)

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