Plants used in traditional medicine in eastern tanzania. V. Angiosperms (passifloraceae to sapindaceae)

Securidaca longipedunculata Fresen (Polygalaceae): A review of its ethnomedicinal uses, phytochemistry, pharmacological properties and toxicology

“…A root decoction may also be drunk to treat fever, malaria, hernias, gonorrhoea, palpitations, headaches, oedema, rheumatism, diabetes, sexual impotence, toothache, fungal infections and malaria (Maroyi, 2013;Ogunmefun and Gbile, 2012;Chhabra et al, 1991;Moshi et al, 2007). …”

Phytotherapeutical implications in pain perception - focusing on schizophrenia

“…Aqueous extract from leavesantinociceptive actions [59] leaf ethanolic extract -in vitro antioxidant activity associated to in vivo hepatoprotective potential [131,132,133] treatment of rheumatisms and Chagas disease [134] Solanum kwebense (Solanaceae) --cerebellar cortical substance degeneration, involving selectively Purkinje neurons [65] abdominal pain, inflammation and rheumatism [32] Xeromohis nilotica (Rubiaceae) aqueous extract from root bark -antinociceptive effect [61] aqueous extract from root bark-short antiinflammatory quality [61]; rootbark extracts -sedative activities [135,136]; antischistosomal [137], molluscidal [138] activities pain, fever, epilepsy and mental disorder [139,140] Consequently, if we take into consideration that synergism between cannabinoids and opioids modulates performance in the fight against pain by targeting multiple pain mechanisms and also the aforementioned antipsychotic and antinociceptive proprieties of cannabidiol and the involvement of opioid mechanisms in pain and schizophrenia, we might be looking at the beginning of a new era in the treatment of pain, but also in the battle against schizophrenia, this complex severe mental illness with modified perception of pain.…”

(4-Methoxy-benzo[1,3]dioxol-5-yl)- <i> Phenylmethanone</i>: an antibacterial benzophenone from securidaca longepedunculata

“…Information from the literature indicates that a decoction of the dried bark is used to treat bacterial infections (de Tommasi et al, 1993;Arnold and Gulumian, 1984), inflammation (de Tommasi et al, 1993), insanity and epilepsy (Mathias, 1982). The leaves are used for treating wounds and sores, cough, venereal diseases, snake bite and as a purgative (Chhabra et al, 1991;Hedberg et al, 1983). They are also used to treat tuberculosis (Asres et al, 2001), bilharzia (Kamwendo et al, 1985), rheumatism (Akah and Nwambie, 1994;Asres et al, 2001), skin diseases (Odebiyi, 1978), headache and mental illness (Msonthi and Magombo, 1983), including convulsions in children (Sofowora, 1980).…”

“…They are also used to treat tuberculosis (Asres et al, 2001), bilharzia (Kamwendo et al, 1985), rheumatism (Akah and Nwambie, 1994;Asres et al, 2001), skin diseases (Odebiyi, 1978), headache and mental illness (Msonthi and Magombo, 1983), including convulsions in children (Sofowora, 1980). The root decoction is used to hasten labour (Kokwaro, 1976;Yu, 1982), to treat malaria (Chhabra et al, 1991), rheumatism (Kloos et al, 1978), gonorrhea, palpitations, pneumonia, syphilis (Desta, 1993), and asthma (Akah et al, 1997).…”