“…Micro-patterning biomedical surfaces by plasma Cells are sensible to topographic and chemical features of sub-micrometric dimensions [16,18]; random and geometrical micro-and nano-metric patterns transferred at the surface of biomedical polymers are known for their ability, in certain contests, of driving the adhesion, motion, spreading and growth steps of cells at their surface. This effect, known as "contact guidance", is quite far, yet, from being completely understood, but could be utilized in a number of fundamental studies and practical applications for biosensors, diagnostic kits and tissue engineering [13][14][15][16][17][18]. Experiments in this last field, for example, include the use of surface-patterned biodegradable polymers as scaffolds for cell cultures.…”