Plasma cholesterol after myocardial infarction

Cotton, Susan G.

doi:10.1136/pgmj.46.539.551

Cited by 9 publications

(2 citation statements)

References 5 publications

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“…According to carlier reports, serum cholesterol had usually returned to preinfarction levels about 3 months after infarction (Tibblin and Cramer, 1963;Cotton, 1970;Fyfe et al, 1971). As we had found the same results in patients controlled by us we used the values from the check-up 3 months after the myocardial infarct (unpublished observations).…”

Section: Study Population and Methodsmentioning

confidence: 85%

Multiple risk prediction of myocardial infarction in women as compared with men.

Wilhelmsen¹,

Bengtsson²,

Elmfeldt³

et al. 1977

Heart

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A study was undertaken to determine whether women who suffer a myocardial infarction in spite of the low frequency in this sex, are more heavily burdened by coronary riskfactors than other women The multivariate risk, based on cholesterol level, systolic blood pressure, and smoking habits, in the women with infarction was very similar to that in the men with myocardial infarction. There was no major difference in risk between pre-and postmenopausal women. A higher prevalence of diabetes mellitus in the women with infarction compared with the general population could not explain their increased risk for myocardial infarction. Thus, other factors must be operating in addition to the traditional risk factors.The incidence of myocardial infarction is higher in men than in women. From a Myocardial Infarction Register, we found the incidence to be about 6 times higher in men than in women in the age group 45 to 54 years (Elmfeldt et al., 1975a). The prevalence of angina pectoris as determined by a questionnaire was, however, similar in the two sexes (Bengtsson, 1969). Because of the low incidence of myocardial infarction in women, few population studies have been able to give an indication of prospective risk factors for this disease in women. In most communities, the only way of finding risk factors in women would be to perform well-designed case control studies.In the Framingham study (Kannel and Castelli, 1972), it was found that the same risk factors seem to operate in women as in men. It has been found that the mean age at the menopause was somewhat lower among women with myocardial infarction than among women in general population samples of similar age (Bengtsson, 1973;Kannel et al., 1975). In a report on myocardial infarction women several of the patients were still menstruating (Bengtsson, 1973), suggesting the protective effect Received for publication 14 April 1977 of the female hormone pattern can be nullified. A question of relevance in this connection is whether those women who suffer a myocardial infarct, but who are still menstruating, are more heavily burdened by coronary risk factors than other women and men of similar age.The present paper reports some data concerning multivariate risk prediction based on serum cholesterol level, systolic blood pressure, and smoking habits, with the aim of comparing the risk factor profile in the male and female population and in men and women who had suffered a myocardial infarct. Prospective data from a population study in men were available (Wilhelmsen et al., 1973).

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Section: Study Population and Methodsmentioning

confidence: 85%

Multiple risk prediction of myocardial infarction in women as compared with men.

Wilhelmsen¹,

Bengtsson²,

Elmfeldt³

et al. 1977

Heart

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show abstract

“…This step was considered desirable, and justifiable in so far as the technique of blood pressure measurement was essentially unchanged. It was not possible similarly to substitute serum cholesterol levels obtained before beginning hypolipidaemic therapy in the 9 patients on such treatment, because the method for cholesterol assay used during the survey was substantially different from that used previously, and plasma levels taken within a few weeks of acute myocardial infarction are not necessarily representative of subsequent stable levels (Cotton, 1970). Accordingly, data from these 9 subjects were excluded from the analysis.…”

Section: Methodsmentioning

confidence: 99%

Factors discriminating men with coronary heart disease from healthy controls.

Cotton¹,

Nixon²,

Carpenter³

et al. 1972

Heart

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In our study, 9I men, under 65 years of age, with clinically overt coronary heart disease were compared with 98 healthy men in respect of fasting plasma cholesterol, triglyceride and other lipid moieties, relevant past andfamily history, smoking habits, a ponderal index, blood pressure, and prevalence of corneal arcus, xanthomata, and baldness. Some dietary aspects were also taken into account.The analysis showed that the main discriminators were diastolic blood pressure, arcus, baldness, xanthelasma, a family history of hypertension, past smoking habits, and hyperlipidaemia. Of these factors, diastolic hypertension emerges as much the most important.

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Predictable changes in low density lipoprotein composition after acute myocardial infarction

Sniderman

Teng

1977

Atherosclerosis

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Plasma cholesterol after myocardial infarction

Cited by 9 publications

References 5 publications

Multiple risk prediction of myocardial infarction in women as compared with men.

Multiple risk prediction of myocardial infarction in women as compared with men.

Factors discriminating men with coronary heart disease from healthy controls.

Predictable changes in low density lipoprotein composition after acute myocardial infarction

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