Plasma circulatory markers in male and female patients with coronary artery disease

Association of influenza virus infection and inflammatory cytokines with acute myocardial infarction

“…This is especially evident because levels of IL-2, IL-6, IL-10, IL-18, TNF-a, IFN-c, ET-1, sICAM-1 and sVCAM-1 were significantly higher in the case group than in the control group (Table 4). This finding is consistent with Jha et al's [22] observation that inflammatory cytokines might take part in the development of atherosclerosis and trigger the occurrence of AMI. It is of particular note that C-reactive protein (CRP) is an extremely important indicator of atherosclerosis due to its diagnostic and predictive capabilities (Table 3).…”

Virtual Histology Evaluation of Atherosclerosis Regression During Atorvastatin and Ezetimibe Administration - HEAVEN Study -

“…The reason why we saw an increase in hsCRP in both groups is unclear, but it may be related to the large number of smokers in both groups (68.3% in A and 61.7% in S group) because a higher level of hsCRP is described in smokers with CAD. 32 The level of hsCRP did not correlate with plaque volume or plaque composition, and a similar finding was reported by Park et al 33 All other markers decreased during the present study, but differences between groups and differences between baseline and follow-up were not significant.…”

Vascular Cell Adhesion Molecule-1 Expression and Signaling During Disease: Regulation by Reactive Oxygen Species and Antioxidants

“…VCAM-1 can also be released from the endothelial surface through cleavage by a disintegrin and metalloprotease 17 (ADAM17) (97) and, although less characterized, may be released by ADAM8 (185,186) or ADAM9 (103,222). Therefore, VCAM-1 is present in the plasma in a soluble form (sVCAM-1) and is used as predictive biomarker of disease (17,127,154,297,319). Levels of sVCAM-1 in plasma increase with activation of the endothelium in multiple diseases (44,55,89,98,133,154,206,219,227).…”