1978
DOI: 10.1093/clinchem/24.10.1830
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Plasma estriol vs. estrogen assays in 24-h urines as an index to fetal status.

Abstract: Conventionally, urinary estrogens are measured to monitor fetal well-being in the third trimester of pregnancy. There are many theoretical and practical advantages to the use of recently introduced plasma estriol assays; consequently, we undertook to compare the results of a spectrophotometric assay for total urinary estrogen with values for plasma total and free (unconjugated) estriol obtained by radioimmunoassay with commercially available kits. The data correlate well, r = 0.70 for plasma total estriol with… Show more

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Cited by 6 publications
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“…The mean within-week CV from 30 to 37 weeks gestation was 25% (range 19-32%; 3 10 measurements). It has been proposed that a fall in plasma oestriol concentration which is greater than 40% of the mean of the three preceding determinations might be used as an index of fetal compromise (Katagiri et al 1976;Kirkish et al 1978;Hagerman 1979). Table 2 shows the frequency with which measured day-to-day decreases in salivary oestriol concentrations in normal and diabetic pregnancies exceeded the preceding mean by a given percentage.…”
Section: Resultsmentioning
confidence: 99%
“…The mean within-week CV from 30 to 37 weeks gestation was 25% (range 19-32%; 3 10 measurements). It has been proposed that a fall in plasma oestriol concentration which is greater than 40% of the mean of the three preceding determinations might be used as an index of fetal compromise (Katagiri et al 1976;Kirkish et al 1978;Hagerman 1979). Table 2 shows the frequency with which measured day-to-day decreases in salivary oestriol concentrations in normal and diabetic pregnancies exceeded the preceding mean by a given percentage.…”
Section: Resultsmentioning
confidence: 99%