2017
DOI: 10.4172/neuropsychiatry.1000288
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Plasma Fibrinogen: An Independent Risk Factor for Post- Stroke Depression

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Cited by 2 publications
(2 citation statements)
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“…Furthermore, as mentioned above, IL-6 was also secreted in response to FG and elevation of this cytokine has been implicated in a number of neurodegenerative diseases including AD ( Rothaug et al, 2016 ). Increasing evidence links changes in brain parenchymal and plasma levels of fibrinogen with microglial and inflammatory responses in a number of neurodegenerative diseases including multiple sclerosis ( Adams et al, 2007 ; Ryu and McLarnon, 2009 ; Acuňa et al, 2017 ) and Alzheimer’s disease ( Cortes-Canteli et al, 2012 ) and following stroke ( Luan et al, 2017 ). Here we present new evidence of a pathway activated in microglia by fibrinogen which has ramifications for neuronal survival and which has not yet been observed in these conditions.…”
Section: Discussionmentioning
confidence: 99%
“…Furthermore, as mentioned above, IL-6 was also secreted in response to FG and elevation of this cytokine has been implicated in a number of neurodegenerative diseases including AD ( Rothaug et al, 2016 ). Increasing evidence links changes in brain parenchymal and plasma levels of fibrinogen with microglial and inflammatory responses in a number of neurodegenerative diseases including multiple sclerosis ( Adams et al, 2007 ; Ryu and McLarnon, 2009 ; Acuňa et al, 2017 ) and Alzheimer’s disease ( Cortes-Canteli et al, 2012 ) and following stroke ( Luan et al, 2017 ). Here we present new evidence of a pathway activated in microglia by fibrinogen which has ramifications for neuronal survival and which has not yet been observed in these conditions.…”
Section: Discussionmentioning
confidence: 99%
“…Luan et al prospectively investigated the effects of baseline fibrinogen levels in more than 400 acute stroke patients regardless of aetiology and proposed its potential utility as a biomarker for PSD. 65 …”
Section: Stroke Happiness and Positive Affectmentioning
confidence: 99%