Plasma homocysteine is associated with ischemic findings without organic stenosis in patients with slow coronary flow

Abstract

The results of this study show that there is an important pathophysiologic link between the increased levels of plasma Hcy, the degree of ischemic findings, and the severity of slow flow in SCF patients.

Heart rate recovery after exercise and its relation with neutrophil-to-lymphocyte ratio in patients with cardiac syndrome X

“…Although PLR was not as strong a predictor as NLR for lower HRR value, it was found to be significantly associated with NLR and HRR, suggesting the presence of a crucial link between inflammatory reactions and autonomic function in the CSX patients analyzed. Similarly, Timurkaynak et al [9] reported that the homocysteine level, known to be related with endothelial dysfunction and ischemic findings [31], was inversely correlated with DTS in patients with CSX, and our findings are in line with these reports. Our study extends these findings in two important ways.…”

Admission homocysteine is an independent predictor of spontaneous reperfusion and early infarct-related artery patency before primary percutaneous coronary intervention in ST-segment elevation myocardial infarction

“…Angiographic findings demonstrated that HHCY was strongly correlated with slow coronary flow (SCF) phenomenon after PCI protacol [ 27 , 28 ], implying the possible correlation between HHCY and less IRA patency. Current evidence suggests that the microcirculation dysfunction and damage of endothelial cells caused by HCY-induced oxidative stress played an important role in SCF [ 29 – 31 ].…”

Low diastolic blood pressure was one of the independent predictors of ischemia-like findings of electrocardiogram in patients who underwent coronary angiography

“…hypertension, diabetes mellitus, dyslipidemia, hyperuricemia, smoking, chronic kidney disease), there were no significant factors associated with ischemia-like ECG. Further investigation involving a larger number of patients and more risk factors, such as high-sensitive C-reactive protein or homocysteine [36], may be needed.…”