Plasma LDL and HDL characteristics and carotenoid content are positively influenced by egg consumption in an elderly population1

Greene, Carolyn A.; Waters, David D.; Clark, Richard M.; Contois, John H.; Fernández, María Luz

doi:10.1186/1743-7075-3-6

Cited by 74 publications

(49 citation statements)

References 57 publications

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“…The significance of responders and nonresponders becomes clear in the studies conducted by Greene et al [131,132] (LOE Ib). In a randomised crossover study on 29 postmenopausal women and 13 men aged over 60, the effect of consuming 3 large eggs daily (equivalent to a daily intake of 640 mg of cholesterol) was examined in comparison to a cholesterol and fat-free substitute [131] (LOE Ib).…”

Section: Quantity and Quality Of Dietary Fat And Fatty Acid Intake mentioning

confidence: 98%

“…The intervention led to an increase in total, LDL and HDL cholesterol concentration, whereas the ratios of LDL to HDL cholesterol and of total to HDL cholesterol were unchanged, as was the triglyceride concentration. A detailed evaluation showed that a significant increase in total, LDL and HDL cholesterol concentration was observed only in 15-42 study participants, who were classified accordingly as hyper responders [131,132] (LOE Ib). In an expanded evaluation, the effects were attributed above all to changes in the distribution and frequency of individual subfractions within the lipoprotein classes [132] (LOE Ib).…”

Section: Quantity and Quality Of Dietary Fat And Fatty Acid Intake mentioning

confidence: 99%

“…A detailed evaluation showed that a significant increase in total, LDL and HDL cholesterol concentration was observed only in 15-42 study participants, who were classified accordingly as hyper responders [131,132] (LOE Ib). In an expanded evaluation, the effects were attributed above all to changes in the distribution and frequency of individual subfractions within the lipoprotein classes [132] (LOE Ib). In an intervention study on 53 men and 72 women aged 22-70, Wolff et al [126] (LOE Ib) were able to show that a low-fat, low-cholesterol Mediterranean diet only resulted in a decrease in the concentrations of total, HDL and LDL cholesterol in persons classified as low cholesterol absorbers.…”

Section: Quantity and Quality Of Dietary Fat And Fatty Acid Intake mentioning

confidence: 99%

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Evidence-Based Guideline of the German Nutrition Society: Fat Intake and Prevention of Selected Nutrition-Related Diseases

Wolfram

Bechthold²,

Boeing

et al. 2015

Ann Nutr Metab

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As nutrition-related chronic diseases have become more and more frequent, the importance of dietary prevention has also increased. Dietary fat plays a major role in human nutrition, and modification of fat and/or fatty acid intake could have a preventive potential. The aim of the guideline of the German Nutrition Society (DGE) was to systematically evaluate the evidence for the prevention of the widespread diseases obesity, type 2 diabetes mellitus, dyslipoproteinaemia, hypertension, metabolic syndrome, coronary heart disease (CHD), stroke, and cancer through the intake of fat or fatty acids. The main results can be summarized as follows: it was concluded with convincing evidence that a reduced intake of total and saturated fat as well as a larger intake of polyunsaturated fatty acids (PUFA) at the expense of saturated fatty acids (SFA) reduces the concentration of total and low-density lipoprotein cholesterol in plasma. Furthermore, there is convincing evidence that a high intake of trans fatty acids increases risk of dyslipoproteinaemia and that a high intake of long-chain polyunsaturated n-3 fatty acids reduces the triglyceride concentration in plasma. A high fat intake increases the risk of obesity with probable evidence when total energy intake is not controlled for (ad libitum diet). When energy intake is controlled for, there is probable evidence for no association between fat intake and risk of obesity. A larger intake of PUFA at the expense of SFA reduces risk of CHD with probable evidence. Furthermore, there is probable evidence that a high intake of long-chain polyunsaturated n-3 fatty acids reduces risk of hypertension and CHD. With probable evidence, a high trans fatty acid intake increases risk of CHD. The practical consequences for current dietary recommendations are described at the end of this article.

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Section: Quantity and Quality Of Dietary Fat And Fatty Acid Intake mentioning

confidence: 98%

Section: Quantity and Quality Of Dietary Fat And Fatty Acid Intake mentioning

confidence: 99%

Section: Quantity and Quality Of Dietary Fat And Fatty Acid Intake mentioning

confidence: 99%

See 1 more Smart Citation

Evidence-Based Guideline of the German Nutrition Society: Fat Intake and Prevention of Selected Nutrition-Related Diseases

Wolfram

Bechthold²,

Boeing

et al. 2015

Ann Nutr Metab

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“…Non-polar carotenoids such as β-carotene and lycopene are associated primarily with VLDL and LDL, while more polar xanthophylls such as lutein and zeaxanthin prefer to associate with HDL [62]. Once loaded with carotenoids, the apolipoprotein components of lipoproteins are thought to help direct the carotenoids to their target tissues via their interactions with specific cell surface receptors.…”

Section: Plasma Carotenoid Binding Proteinsmentioning

confidence: 99%

Vertebrate and invertebrate carotenoid-binding proteins

Bhosale

Bernstein

2007

Archives of Biochemistry and Biophysics

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In invertebrates and vertebrates, carotenoids are ubiquitous colorants, antioxidants, and provitamin A compounds that must be absorbed from dietary sources and transported to target tissues where they are taken up and stabilized to perform their physiological functions. These processes occur in a specific and regulated manner mediated by high-affinity carotenoid-binding proteins. In this minireview, we examine the published literature on carotenoid-binding proteins in vertebrate and invertebrate systems, and we report our initial purification and characterization of a novel luteinbinding protein isolated from liver of Japanese quail (Coturnix japonica).

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“…Some studies have demonstrated that supplementation with eggs, as a source of dietary carotenoids, positively modulates plasma carotenoid and lipoprotein subclasses [19,20]. However, to the best of our knowledge, there is no information about the effect of a Mediterranean-style low-glycemic-load diet on OxLDL levels in women with MetS.…”

Section: Introductionmentioning

confidence: 99%

A Mediterranean-style low-glycemic-load diet increases plasma carotenoids and decreases LDL oxidation in women with metabolic syndrome

Barona

Jones

Kopec

et al. 2012

The Journal of Nutritional Biochemistry

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Thirty-five women with metabolic syndrome and high plasma low-density lipoprotein (LDL) cholesterol (≥100 mg/dl) participated in a dietary intervention consisting of a Mediterranean-style low-glycemic-load diet for 12 weeks. Participants were randomly allocated to consume diet only (n=15) or diet plus a medical food containing soy protein and plant sterols (n=20). Plasma concentrations of carotenoids, lipoprotein subfractions and oxidized LDL (OxLDL) were measured. Independent of treatment, women had a significant increase in plasma lutein (P<.0001) and β-carotene (P<.0001), while plasma lycopene was reduced (P<.05) after 12 weeks. Low-density lipoprotein cholesterol was reduced from 138±35 to 114±33 mg/dl (P<.0001). In addition, decreases were observed in the atherogenic subfractions: large very low-density lipoprotein (P<.05), small LDL (P<.00001) and medium high-density lipoprotein (P<.05). Oxidized LDL was significantly reduced by 12% in both groups (P<.01). Changes in OxLDL were inversely correlated with plasma lutein (r=−.478, P<.0001). The data indicate that women complied with the dietary regimen by increasing fruits and vegetable intake. Decreased consumption of high-glycemic foods frequently co-consumed with lycopene-rich tomato sauce such as pasta and pizza may be responsible for the lowering of this carotenoid in plasma after 12 weeks. These results also suggest that plasma lutein concentrations may protect against oxidative stress by reducing the concentrations of OxLDL.

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Plasma LDL and HDL characteristics and carotenoid content are positively influenced by egg consumption in an elderly population1

Cited by 74 publications

References 57 publications

Evidence-Based Guideline of the German Nutrition Society: Fat Intake and Prevention of Selected Nutrition-Related Diseases

Evidence-Based Guideline of the German Nutrition Society: Fat Intake and Prevention of Selected Nutrition-Related Diseases

Vertebrate and invertebrate carotenoid-binding proteins

A Mediterranean-style low-glycemic-load diet increases plasma carotenoids and decreases LDL oxidation in women with metabolic syndrome

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