Plasma lipids, blood coagulation and fibrinolysis in peripheral arterial disease

Abstract

SummaryIn a study relating platelet stickiness, plasma fibrinogen and fibrinolysis to fasting plasma lipids in patients with atherosclerosis of the lower limbs, a significant correlation has been observed between platelet stickiness and plasma phospholipid levels. The possible mechanisms are discussed. No other correlation is observed. Fasting levels of plasma fibrinogen were raised, while levels of plasminogen, and the degree of platelet stickiness in many cases were normal.

Significance of hemorrheology in the management of the ischemic limb

“…On the other hand, many vascular surgeons believe that the more hemoglobin, the better. Similarly, the longer term failure of femoro-popliteal reconstructions has been shown to be associated with an elevated plasma fibrinogen concentration during this period [18]. The healing of ischemic skin flaps also seems to be related to the preoperative hemoglobin concentration.…”