Plasma Protein Adsorption and Platelet Adhesion on Poly[bis(trifluoroethoxy)phosphazene] and Reference Material Surfaces

Welle, Alexander; Grunze, M.; Tur, D. R.

doi:10.1006/jcis.1997.5238

Cited by 72 publications

(64 citation statements)

References 43 publications

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“…Although the glutaraldehyde in GC may crosslink some of the amino groups of chitosan which carry positive charges in neutral solution, there are some aldehyde groups on the surface of GC which may bind proteins via their amino groups by the formation of an azomethine bond. 20 This compensation led to the similarity between the value of A 490 of Chi and GC in fibronectin and laminin adsorption. Surprisingly, CPL, the material with a wettability a little less than Chi and surface positive charges comparable to Chi, had higher A 490 in both laminin and fibronectin adsorption than Chi.…”

Section: Discussionmentioning

confidence: 99%

Studies on nerve cell affinity of chitosan-derived materials

Gong

Zhong

et al. 2000

J. Biomed. Mater. Res.

166

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Reparation of the central nervous system (CNS) is important because when it is impaired its recovery is difficult and concomitant malfunction of other parts of body occurs. In our previous studies, chitosan was found to be a good material supporting nerve repair. The purpose of this article was to study the ability of chitosan and some chitosan-derived materials to facilitate the growth of nerve cells. Those materials were chitosan, glutaraldehyde-crosslinked chitosan, glutaraldehyde-crosslinked chitosan-gelatin conjugate, a chitosan-gelatin mixture, chitosan coated with polylysine (CAP), and a chitosan-polylysine mixture (CPL). Gelatin and polylysine were used as controls. After nerve cells (gliosarcoma cells and normal cerebral cells) were grown on those materials, their attachment, spread, and growth were observed. The adsorption of some extracellular matrix molecules such as laminin and fibronectin on the materials and the role the molecules play in nerve cell attachment and spreading were also studied by enzyme-linked immunosorbent assay and MTT method. We found that both CAP and CPL have excellent nerve cell affinity, defined as the ability to promote nerve cell to grow and function normally. Those two materials may be promising for the repair of the nervous system. Materials precoated with laminin, fibronectin, and serum were analyzed for their nerve cell affinity. Results suggest that after being precoated with laminin and fibronectin solution or serum, all material have better nerve cell affinity.

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Section: Discussionmentioning

confidence: 99%

Studies on nerve cell affinity of chitosan-derived materials

Gong

Zhong

et al. 2000

J. Biomed. Mater. Res.

166

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“…Adsorption of biomolecules on implant surfaces is an important phenomenon with respect to the biocompatibility of prostheses (1)(2)(3)(4). Much research has been directed toward investigations of protein adsorption at surfaces with different physical and chemical properties to gain a better understanding of factors determining biocompatibility.…”

Section: Introductionmentioning

confidence: 99%

An in Situ Infrared Spectroscopic Investigation of Lysine Peptide and Polylysine Adsorption to TiO2 from Aqueous Solutions

Roddick-Lanzilotta

McQuillan

1999

Journal of Colloid and Interface Science

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“…Uchida et al also reported that platelet adhesion was inhibited on the HA film containing albumin formed by the Ca-P coprecipitation method [17]. Albumin adsorbed materials are known to show better blood compatibility [31,32].…”

Section: Measurement Of Clot Formationmentioning

confidence: 96%