Plasma rico en plaquetas en el tratamiento del fotodaño cutáneo en las manos

Cabrera-Ramírez, J.O.; Puebla-Mora, Ana Graciela; González-Ojeda, Alejandro; Garcia-Martínez, David; Cortés-Lares, José Antonio; Márquez-Valdés, A.R.; Contreras-Hernández, Guadalupe Ivette; Bracamontes-Blanco, J.; Ortíz, Jorge

doi:10.1016/j.ad.2017.04.006

Cited by 14 publications

(2 citation statements)

References 19 publications

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“…Cabrera-Ramírez JO et al applied 3 subcutaneous PRP sessions with a cannula on the back of the hands. At the end of the treatment, the subjects had clinical improvement in the Fitzpatrick wrinkle and elastosis classification scale (p <0.001) and in the Glogau photodamage scale (p = 0.01) and a histological increase in the number of fibroblasts (p = 0.000), number of vessels (p = 0.000) and amount of collagen (p = 0.27) [13].…”

Section: Discussionmentioning

confidence: 99%

Treatment of cutaneous photoaging lesions with autologous platelet concentrate

León¹,

Trujillo²,

Novo³

et al. 2022

Arch Clin Trials

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Background: Facial aging causes a devastating physical and mental impact on quality of life. Objective: To evaluate the efficacy and safety of autologous platelet concentrate (APC) in the treatment of cutaneous photoaging (SCF). Method: Between March 1, 2017 and March 31, 2021, at the “Hermanos Ameijeiras” hospital, a randomized, single-center, double-blind and controlled clinical trial was carried out in 164 patients with ECF. A group treated with CPA was compared to another treated with fresh autologous plasma (AFP). The treatment was applied monthly for 1 year. Results: Three months after the end of the treatment, there were significant differences between the patients treated with CPA compared to those treated with PFA in terms of the improvement in the degree of photodamage and the degree of satisfaction (p <0.001). All adverse events were of mild intensity, did not imply changes before the intervention and were completely resolved. Conclusions: The autologous platelet concentrate proved to be effective and safe to reduce the signs of skin aging, associated with a high degree of patient satisfaction.

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Section: Discussionmentioning

confidence: 99%

Treatment of cutaneous photoaging lesions with autologous platelet concentrate

León¹,

Trujillo²,

Novo³

et al. 2022

Arch Clin Trials

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“…9,10 To enhance the texture and decrease hyperpigmentation and discoloration of the dorsum of the hand, resurfacing by energy-and light-based devices as lasers or injections of platelet rich plasma can be used. 11,12 Injecting hyaluronic acid-based soft tissue fillers or calcium hydroxyapatite can replenish volume and consecutively rejuvenate the hand. A recent investigation has shown that by respecting the underlying layered anatomy of the dorsum of the hand, the incidence of risks such as hematoma and bruising or formation of granulomas is very low and injections of soft-tissue fillers into the dorsum of the hand can be considered safe and efficient.…”

Section: Introductionmentioning

confidence: 99%

Validated 5 – Point photonumeric scales for the assessment of hand atrophy

Green

Pavicic²,

Pooth

et al. 2022

J of Cosmetic Dermatology

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Objective: Quantifying the degree of dorsal hand atrophy is a challenging endeavor, but often necessary, in both the clinical and the research setting. The aim of this investigation was to create and consecutively validate a 5-point photonumeric scale for assessment of dorsal hand atrophy. Material and Methods:A medical team created a novel 5-point photonumeric scale.Twelve international raters were involved in the digital validation, while five raters performed a live validation. Results:For the digital validation of the Croma Hand Atrophy Assessment Scale, a total of 72 subjects (58 females, 14 males) with a mean age of 43.0 ± 14.4 years [18-73 years] were assessed. For the live validation, 88 subjects (73 females, 15 males) with a mean age of 45.0 ± 14.1 years [20-73 years] were rated. The results revealed almost perfect intra-rater (ICC: 0.90 [95% CI: 0.88-0.92]) and inter-rater agreements

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Effect of Platelet-Rich Plasma Injection for Rejuvenation of Photoaged Facial Skin

et al. 2018

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IMPORTANCE There remains little experimental evidence and no randomized clinical trial to date to confirm the benefit of platelet-rich plasma (PRP) for facial rejuvenation. OBJECTIVE To investigate whether PRP injection improves the visual appearance, including texture and color, of photodamaged facial skin. DESIGN, SETTING, AND PARTICIPANTS In this randomized clinical trial, participants and raters were masked to groupings. The setting was an academic-based, urban outpatient dermatology practice in Chicago, Illinois. Participants were adults aged 18 to 70 years with bilateral cheek rhytids of Glogau class II or greater. The duration of the study was August 21, 2012, to February 16, 2016. INTERVENTIONS Each participant received 3 mL intradermal injections of PRP to one cheek and sterile normal saline to the contralateral cheek. MAIN OUTCOMES AND MEASURES Primary outcomes were photoaging scores (with subscores for fine lines, mottled pigmentation, roughness, and sallowness) as rated by 2 masked dermatologists. Secondary outcomes included participant self-assessment scores of improvement on a 5-point scale (worsening, no change, mild improvement, moderate improvement, or significant improvement), participant overall satisfaction scores on a 4-point scale (not satisfied, slightly satisfied, moderately satisfied, or very satisfied), and participant-reported or investigator-observed adverse events. RESULTS Of 27 enrolled participants, 19 (mean [SD] age, 46.37 [10.88] years; 17 female) were analyzed. Reported adverse events, which were not associated with the study agent, included redness (n = 18), swelling (n = 16), bruising (n = 14), pruritus (n = 1), skin scaling (n = 1), and dryness of skin (n = 1). No participants reported any adverse events at 12 months. Mean (SD) photoaging scores rated by 2 dermatologists showed no significant difference between PRP and normal saline for fine lines (baseline, 1.

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Plasma rico en plaquetas en el tratamiento del fotodaño cutáneo en las manos

Cited by 14 publications

References 19 publications

Treatment of cutaneous photoaging lesions with autologous platelet concentrate

Treatment of cutaneous photoaging lesions with autologous platelet concentrate

Validated 5 – Point photonumeric scales for the assessment of hand atrophy

Effect of Platelet-Rich Plasma Injection for Rejuvenation of Photoaged Facial Skin

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