Plasma rico en plaquetas: fundamentos biológicos y aplicaciones en cirugía maxilofacial y estética facial

Flores, Jordi Rodríguez; Gallego, María Angustias Palomar; Torres, Juan Ramón Fernández

doi:10.1016/j.maxilo.2011.10.007

Cited by 29 publications

(35 citation statements)

References 38 publications

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“…This being an autologous product, the risk for viral infection and autoimmune response is averted. Its usefulness has been demonstrated in several specialties (urology, thoracic and cardiac surgery, and plastic surgery) (7)(8)(9)(10)(11)(12)(13).…”

Section: Discussionmentioning

confidence: 99%

“…Multiple clinical experiences have been collected with the use of autologous platelet-rich plasma (PRP), initially in the setting of maxillofacial surgery (7) for the repair of tumor resection-related defects; the technique was then endorsed in other specialties such as chest surgery (8), cardiovascular surgery (9), plastic surgery (10), traumatology (11), and nephrology (12).…”

Section: Introductionmentioning

confidence: 99%

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Using autologous platelet-rich plasma for the treatment of complex fistulas

Moreno-Serrano¹,

García-Díaz²,

Ferrer-Márquez³

et al. 2016

Rev Esp Enferm Dig

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Objective:This study aims to demonstrate the effectiveness and safety of autologous fibrin gel rich in platelet growth factors for the treatment of complex perianal fistulas.Material and methods: Prospective epidemiological study. Patients with complex perianal fistula or perianal fistula mere alteration of continence are included. identification of both holes and the journey, curettage of it and instillation of Vivostat PRF ® in the way it is done to observe excess material by OFE. The variables analyzed were: age, sex, use of prior Seton clinic prevalent type of fistula, postoperative complications, fistula closure and impaired quality of life using the SF-36 test (v2).Results: From January 2011 to May 2013 have involved 23 patients, 12 men and 11 women, with an average age of 49 years and a minimum follow-up of 12 months. Two dropped out. 17 patients had low transsphincteric fistulas, 2 and 2 high transsphincteric intersphincteric with impaired continence. The most common symptom is the discharge. Twelve patients had a loose seton (62%), of which nine cured. Of all the patients we have operated the success rate is 62%. No patient developed incontinence after treatment. Only two reported a worse quality of life after surgery.Conclusion: This study demonstrates that there is a clear benefit to the use of Vivostat PRF ® as a treatment for complex perianal fistulas. It is a highly reproducible technique with acceptable results and does not produce impairment of continence.

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Using autologous platelet-rich plasma for the treatment of complex fistulas

Moreno-Serrano¹,

García-Díaz²,

Ferrer-Márquez³

et al. 2016

Rev Esp Enferm Dig

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“…El plasma rico en plaquetas se presenta así como una buena opción frente a estos adhesivos industriales, que tienen propiedades similares de adhesión y hemostasia, pero con mayores costes y también el riesgo, aunque pequeño, de la transmisión viral y reacciones alérgicas 3,7 . La gran popularización del PRP tuvo sus orígenes en los campos de la cirugía oral y la odontología por los efectos estimulantes de este preparado sobre los fibroblastos de la estructura periodontal y la mucosa oral, y sobre los osteblastos del hueso alveolar 8 . Su uso está muy extendido además en otras especialidades por favorecer la curación de heridas quirúrgicas y regenerar tejidos perdidos.…”

Section: Discussionunclassified

“…Actúa no sólo directamente sobre las células diana para los factores de crecimiento, sino también como matriz extracelular para la estimulación de la reparación y/o regeneración del tejido de un modo global. Además se considera que reduce la inflamación postoperatoria y la acumulación de lí-quido, hematoma y seroma debido a las propiedades hemostáticas y antigénicas derivadas de los factores de crecimiento de plaquetas [8][9][10] . En el PRP se aíslan: factor de crecimiento de origen plaquetario (PDGF), factor de crecimiento fibroblástico (FGF), factor de crecimiento similar a la insulina (IGF), factor de crecimiento epidérmico (EGF) y factor de transformación beta ( TGF-β) tipos 1 y 2 5,6-10 .…”

Section: Discussionunclassified

“…Por sus efectos sobre los tejidos blandos, el PRP se ha usado en cirugía plástica y dermatológica para favorecer y modular la curación en los colgajos cutáneos repuestos, ofreciendo una mejor regeneración tisular, un mejor sellado y una mejor hemostasia de todos los procedimientos quirúrgicos que llevan implícito el levantamiento de un colgajo 8 . Sin embargo, hay pocas publicaciones sobre uso de plasma rico en plaquetas en cirugía, particularmente autólogo, con resultados dispares.…”

Section: Discussionunclassified

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Uso Del Plasma Rico en Plaquetas Autólogo en Abdominoplastías

García-García¹,

Lirón-Ruíz²,

Martín-Lorenzo

et al. 2015

Rev Chil Cir

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using platelet rich plasma in abdominoplastyObjective: Evaluation of the effectiveness of autologous platelet rich plasma administered topically in the healing and prevention of complications of abdominoplasty after bariatric surgery. material and methods: The data from 30 patients who underwent abdominoplasty were analyzed: Group I: Rich plasma was administered autologous platelets in the surgery. Group II: Control. Study variables: complications (seroma, local infection and bleeding), length of stay and cost. results: no significant differences were observed in the frequency of complications or length of stay. The use of platelet rich plasma raises the cost of the procedure. conclusion: Even considering the limitations of the study because of its small sample size and lack of blinding, the results do not support the use of this complementary technique. Further studies are needed in the field of adhesives, sealants and local hemostatic.key words: Platelet rich plasma, abdominoplasty, complication.resumen Objetivo: Evaluación de la eficacia del plasma rico en plaquetas autólogo administrado de forma tópica en la cicatrización y prevención de las complicaciones de la abdominoplastía y dermolipectomía tras cirugía bariátrica. material y método: Serie de 30 pacientes afectos de faldón abdominal tras cirugía bariátrica, a los que se practicó dermolipectomía y abdominoplastía, divididos en dos grupos de 15 casos con aletorización simple. Grupo I: Se administró plasma rico en plaquetas autólogo en el lecho quirúrgico. Grupo II: Control. Variables de estudio: complicaciones (seroma, infección local y hemorragia), tiempo de estancia y coste. resultados: no se aprecian diferencias significativas en la frecuencia de complicaciones ni en estancia media. El uso de plasma rico en plaquetas eleva el coste del procedimiento. conclusión: Aun considerando las Rev Chil Cir. Vol 67 -nº 5, Octubre 2015; pág. 506-510 artículO de inVestigaciÓn *Recibido el 8 de septiembre de 2014 y aceptado para publicación el 30 de marzo de 2015.Los autores no refieren conflictos de interés.

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Platelet‐rich plasma, a powerful tool in dermatology

Merchán

Gómez

Chasoy

et al. 2019

J Tissue Eng Regen Med

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Platelet‐rich plasma (PRP), a platelet concentrate contained in a small volume of plasma, has become a promising option in the last decade to treat different diseases related to the skin due to its high concentration of growth factors. When it is of autologous origin, it decreases the probability of suffering adverse reactions and transfusion‐transmitted infections, thus it is an optimal and safe therapy for the patient. PRP has been used in the treatment of several dermatological conditions such as acne, alopecia, and skin ulcers. Its use has also extended to other skin conditions such as melasma, hyperpigmentation, and burns, where it stimulates tissue repair and regeneration. The purpose of this article is to review the management and treatment of different dermatological alterations with PRP. Although there are a variety of studies that support the use of PRP, more research is needed to standardise the protocols for obtaining, processing, and applying it as well as understanding the biological and molecular bases of its functioning.

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Plasma rico en plaquetas: fundamentos biológicos y aplicaciones en cirugía maxilofacial y estética facial

Cited by 29 publications

References 38 publications

Using autologous platelet-rich plasma for the treatment of complex fistulas

Using autologous platelet-rich plasma for the treatment of complex fistulas

Uso Del Plasma Rico en Plaquetas Autólogo en Abdominoplastías

Platelet‐rich plasma, a powerful tool in dermatology

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