Plasma zinc-serum albumin correlation: relevance to assessment of zinc status in humans

Abstract

Summary Plasma zinc and serum albumin were measured in an ostensibly healthy group of volunteers. Calculation of the correlation coefficient showed a small but significant correlation between plasma zinc and serum albumin in the total group studied (r= 0·35, P<0·05), The results indicate that in healthy individuals there is a small but significant correlation between serum filbumin and plasma zinc, but the low degree of correlation would suggest that there are other variables affecting plasma zinc in health. However, the demonstration of this correlation suggests that additional information may be obtained in studies of zinc status by concomitant serum albumin measurement.

The Impact of Hyperthyroidism on Selected Serum Proteins and Metal Ions in the Population of Lahore and Its Surrounding Areas

“…This relationship suggests that a relative reduction in zinc concentration will also lower down the serum albumen concentration. Other studies have also reported a significant correlation between serum zinc and albumin, and a decline in the albumin concentration resulting in the decline of zinc as well [36,37]. Our study is in line with previous studies and it indicates that zinc is involved in the metabolism of proteins [38].…”