Plastic Membrane Selective Electrode for Cetirizinium Ion Based on Cetirizinium-Tetraphenylborate Ion-Pair

Shoukry, A; Abdel‐Ghani, Nour T.; Issa, Y. M.; Ahmed, Howayda M.

doi:10.1002/(sici)1521-4109(199905)11:6<443::aid-elan443>3.0.co;2-j

Cited by 18 publications

(8 citation statements)

References 6 publications

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“…Several membrane composition electrodes as well as graphite, copper, and silver wires (3 mm in diameter and 12 cm in length) were constructed and used as previously described [19].…”

Section: Methodssupporting

confidence: 92%

Potentiometric Flow Injection Analysis of Bromhexine Hydrochloride and its Pharmaceutical Preparation Using Conventional and Coated Wire Ion-Selective Electrodes

2006

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Bromhexine hydrochloridei on-selectivee lectrodes (conventionalt ype)b ased on bromhexinium tetraphenylb orate( I) andb romhexinium-phosphotungstate (II) were prepared.T he electrodes exhibitedm ean slopes of calibration graphs of 59.4 mV and 59.8 mV per decade of bromhexine concentrationa t2 5 Cf or electrode (I) and (II),r espectively.B oth electrodes couldb eu sed within the concentrationr ange 3.16x10-5 -1.00x10 -2 Mb romhexine within the pH range 2.0-4.5. The standard electrodes potentials were determined at different temperatures and used to calculate the isothermal coefficients of the electrodes, which were 0.00065 and 0.00050V C -1 for (I) and (II), respectively. The electrodes showed av ery good selectivity for bromhexine with respect to an umber of inorganic cations, amino acids and sugars. The electrodes were applied to the potentiometric determination of bromhexine hydrochloride and its pharmaceutical preparationu nder batch and flow injection conditions.G raphite, copper and silver coated wires were prepared, characterized and successfully applied as sensors for the drug under investigation. KeywordsIon-selectivee lectrodes, bromhexine hydrochloride, conventional andc oated wire electrodes,flowinjection analysis andconductimetry.Scientia Pharmaceutica (Sci. Pharm.) 74, 121-135

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“…Several membrane composition electrodes as well as graphite, copper, and silver wires (3 mm in diameter and 12 cm in length) were constructed and used as previously described [19].…”

Section: Methodssupporting

confidence: 92%

Potentiometric Flow Injection Analysis of Bromhexine Hydrochloride and its Pharmaceutical Preparation Using Conventional and Coated Wire Ion-Selective Electrodes

2006

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“…Ch-HCl was determined potentiometrically using the investigated electrodes under batch conditions by applying the standard addition [20] and potentiometric titration [21] methods. In the standard addition method known volumes of standard drug solution were added to 50 mL water containing different amounts of pure compound or the pharmaceutical preparations (allergex and allergex caffeine tablets).…”

Section: Potentiometric Determination Of Ch-hclmentioning

confidence: 99%

Flow injection potentiometric determination of Chlorphenoxamine Hydrochloride

Abdel‐Ghani

Hussein

2010

J Appl Electrochem

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New Chlorphenoxamine (Ch) ion selective plastic membrane electrodes for both conventional and coated wire types based on the ion associate of Ch-HCl with sodium tetraphenylborate (NaTPB) and phosphotungestic acid (PTA) were prepared. The conventional type electrode was fully characterized in terms of membrane composition, plasticizer, filling solution, life span, pH, ionic strength, temperature. The membranes of optimum compositions were used for the preparation of both graphite and cupper coated wire electrodes. The prepared electrodes were used for the potentiometric determination of the investigated drug in raw material and pharmaceutical preparations under batch and flow injection analysis conditions. The selectivity of the electrodes towards a large number of excipients like inorganic cations, sugars, amino acids and other antihistaminic drugs was tested. Determination of Ch-HCl, the solubility product of the ion associate and the formation constant of the precipitation reaction leading to the ion associate formation of Ch-HCl with NaTPB and PTA were carried out using conductimetric measurements.

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“…The plastic layer formed on the surface of the rod is left to dry in air and the process was repeated several times (8-12) till a layer of proper thickness is formed covering the terminal of the rod. 20 …”

Section: Electrode Constructionmentioning

confidence: 99%

Flow Injection Analysis with Tubular Membrane Ion‐Selective Electrode and Coated Wires for Buspirone Hydrochloride

et al. 2006

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Summary -New Plastic membrane ion-selective electrode for buspirone hydrochloride based on buspironium tetraphenylborate was prepared. The electrode exhibited mean slope of calibration graph of 58.4 mV per decade of BusCl concentration at 25°C. The electrode can be used within the concentration range 6.3 x10 -5 -10 -2 M BusCl at a pH range of 2.5-7.0. The standard electrode potentials were determined at different temperatures and used to calculate the isothermal temperature coefficient of the electrode, amounting to 0.00056 V°C -1 . The electrode showed a very good selectivity for BusCl with respect to a number of inorganic cations, sugars and amino acids. The electrode was applied to the potentiometric determination of the buspirone ion and its pharmaceutical preparation under batch and flow injection conditions. Also, buspirone was determined by conductimetric titrations. Graphite rod, copper and silver coated wire electrodes were prepared and characterized as sensors for the drug under investigation.

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Plastic Membrane Selective Electrode for Cetirizinium Ion Based on Cetirizinium-Tetraphenylborate Ion-Pair

Cited by 18 publications

References 6 publications

Potentiometric Flow Injection Analysis of Bromhexine Hydrochloride and its Pharmaceutical Preparation Using Conventional and Coated Wire Ion-Selective Electrodes

Potentiometric Flow Injection Analysis of Bromhexine Hydrochloride and its Pharmaceutical Preparation Using Conventional and Coated Wire Ion-Selective Electrodes

Flow injection potentiometric determination of Chlorphenoxamine Hydrochloride

Flow Injection Analysis with Tubular Membrane Ion‐Selective Electrode and Coated Wires for Buspirone Hydrochloride

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