Nature is a master engineer. From the bones of the tiniest bird to the sophisticated bioproduction of a spider’s web, the works of nature are an enigma to the scientific mind. In the fields of physics, chemistry, biology, and mathematics, studying, understanding, and harnessing the intricacies of nature’s designs for the benefit of mankind is the bedrock of science and technology. One such exceptionally engineered natural material is the bamboo plant. This ancient vegetation has, over dozens of generations, reinvented itself as a legendary, resilient, ubiquitous, and impressive bioresource that is not just sustainable, but also ecologically and cheaply cultivatable, and invaluable for soil erosion control, while holding the enormous potential to be transmuted into various useful chemicals and materials. With the increasing concerns and obligations in rethinking the future of the environment, sequestration of carbon dioxide, reduction in timber usage, and preservation of already depleted non-renewable resources, it has become vital for environmentalists, governments, scientists, and other stakeholders to identify alternatives to fossil-based chemicals and their derivable materials that are sustainable without compromising efficiency. By coalescing engineering-, chemical-, and materials science-based approaches, including results from over 100 reports, we demonstrate that the bamboo plant presents enormous opportunities for sustainable chemicals and materials. In addition, we highlight the current challenges involving the optimization of bamboo-based technologies and provide recommendations for future studies.