Platelet Activity in Patients With Third Degree Arterial Hypertension and Metabolic Syndrome

Медведев, И. Н.; Zavalishina, S. Yu.

doi:10.18565/cardio.2016.1.48

Cited by 19 publications

(25 citation statements)

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“…So, density of glycoproteids Ia-IIa and VI, involved into blood-platelet adhesion, gradually increased on the surface of their platelets, as can be seen at PA intensification in response to collagen [32,42]. Increased platelet adhesion in the experimental rats should be associated with overexpression of the receptors to von Willebrand factor on their surface.…”

Section: Discussionmentioning

confidence: 99%

“…Among other reasons, age-related changes can negatively affect rheological properties of blood cells [7,8] and activity of the hemostasis system [9], often resulting in a thrombophilic situation in their body [8,10].…”

Section: Introductionmentioning

confidence: 99%

“…Considering that the surface with activated platelets is a "buffer state" for all hemostasis processes [32], capable of causing occlusion of different vessels [33,34] under poor disaggregating mechanisms, experimental works on the detailed study of the dyslipidemia impact on platelet activity are considered to be of great practical interest. It is hard to trace the earliest stages of hemostatic disorders of platelets in humans because very seldom do doctors observe people with the first signs of dyslipidemia.…”

Section: Introductionmentioning

confidence: 99%

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Platelet-Activity Dependence on the Age of Rats with Experimental Dyslipidemia

Zavalishina¹,

NV²

2016

Biol Med (Aligarh)

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Platelet-Activity Dependence on the Age of Rats with Experimental Dyslipidemia

Zavalishina¹,

NV²

2016

Biol Med (Aligarh)

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“…Activation of platelet aggregation significantly worsens the microcirculation in the capillaries in animals and is dangerous inhibition of growth due to a decrease in metabolism [30,31]. The revealed increase in hemocoagulation activity in the examined piglets evidently occurred during the growth of activity of the main number of coagulation factors, which caused a found increase in blood coagulation along the external path [32].…”

Section: 4±069mentioning

confidence: 99%

Restoring the functional state of the hemostasis system in piglets experiencing an episode of transportation

et al. 2020

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Negative environmental impact can often adversely affect the functional properties of piglets and significantly weaken their viability. It is often possible to judge this by the dynamics of the activity of hemostasis indicators. The level of activity of platelets and coagulation systems very early change activity in the case of negative influences from the outside, causing the appearance of overt hemostasiopathy. This condition leads to the disruption of hemocirculation in the capillaries and a decrease in the severity of metabolism in the tissues. These changes lead to a slowdown in growth and a general weakening of animals, thereby leading to great economic damage. It was found that the appearance of transport stress in piglets leads to increased platelet aggregation and activation of homocoagulation mechanisms during inhibition of fibrinolysis. Due to the fact that this situation is very common, the possibility of eliminating these dysfunctions was studied. The study tested fumaric acid at 0.1 g/kg in the form of a feed additive for 20 days in piglets that underwent long-term transportation. As a result of using this supplement, it was possible to reduce platelet activity and blood coagulation and increase fibrinolysis activity, bringing them to control values. As a result of the study, it was found that the intake of fumaric acid in the body of piglets that have experienced the influence of a high-intensity medium optimizes the functional status of their hemostasis. This minimizes their risk of microthrombosis and weakened animal growth.

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“…Age-specific dynamics of physiological indices of cattle youngsters is mostly connected with ontogenetic changes of their blood parameters [1]. Continuously moving along vessels blood, composing of plasma and its regular elements, fulfils some functions including provision of gas exchange and transportation to tissues of nutrients, hormones, vitamins and so on, and also -washing of final products of metabolism out of them [2,3]. Hemocirculation optimum including vessels of microcirculation system is mostly connected with evidence of regular blood elements' aggregation [4,5] essentially defined by the level of deaggregating control from a vascular wall side.…”

Section: Introductionmentioning

confidence: 99%

Aggregative Activity of Basic Regular Blood Elements and Vascular Disaggregating Control over It in Calves of Milk-vegetable Nutrition

Glagoleva¹,

Zavalishina

2017

ARRB

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Estimation of ontogenetic peculiarities of aggregation of regular blood elements and vascular control over it, including calves in the middle of early ontogenesis -in the phase of milk-vegetable nutrition, is of great scientific and practical interest. Clarification of their physiological balance is really significant for receiving the possibility of regulation of hemostasis activity and metabolism intensity in tissues. To estimate aggregative activity of regular blood elements and disaggregating vessels' control over them in calves during the phase of milk vegetable nutrition. We formed a group of calves of black-many-colored breed which were examined 5 times at the age between the 31st and the 90th days of life with the application of biochemical, hematological and statistical methods of Original Research Article

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Platelet Activity in Patients With Third Degree Arterial Hypertension and Metabolic Syndrome

Cited by 19 publications

References 0 publications

Platelet-Activity Dependence on the Age of Rats with Experimental Dyslipidemia

Platelet-Activity Dependence on the Age of Rats with Experimental Dyslipidemia

Restoring the functional state of the hemostasis system in piglets experiencing an episode of transportation

Aggregative Activity of Basic Regular Blood Elements and Vascular Disaggregating Control over It in Calves of Milk-vegetable Nutrition

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