Platelet-poor plasma-based biofiller: An innovative alternative to expensive hyaluronic acid–based fillers for treatment of chicken pox scars

Dashore, Shuken; Dashore, Anil

doi:10.1016/j.jaad.2019.07.100

Cited by 9 publications

(10 citation statements)

References 2 publications

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“…Recently, PPP gel has been recommended as a successful autologous dermal filler for facial rejuvenation, 14 acne scars, 17 and chicken pox scars. 18 To date, no previous published report was noticed about its therapeutic efficacy in dark circles. Based on the previously suggested lightening effect of PRP in elimination of dark circles, 9,10 we decided to compare the efficacy of PPP gel vs PRP for infraorbital rejuvenation (both tear trough deformity and dark circles).…”

Section: Discussionmentioning

confidence: 99%

“…Among various therapeutic modalities for infraorbital rejuvenation, dermal fillers stand out. Recently, PPP gel has been recommended as a successful autologous dermal filler for facial rejuvenation, 14 acne scars, 17 and chicken pox scars 18 . To date, no previous published report was noticed about its therapeutic efficacy in dark circles.…”

Section: Discussionmentioning

confidence: 99%

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Platelet‐poor plasma gel vs platelet‐rich plasma for infraorbital rejuvenation: A clinical and dermoscopic comparative study

Neinaa

Hodeib

Morquos

et al. 2020

Dermatologic Therapy

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Infraorbital dark circles and tear trough deformity are considered common aesthetic problems. Numerous therapeutic modalities have been suggested with variable outcomes. The aim of this study was to compare the efficacy of platelet-poor plasma (PPP) gel vs platelet-rich plasma (PRP) in infraorbital rejuvenation. A total of 68 females presented with dark circles and/or tear trough deformity were recruited and treated by PPP gel injection in the right infraorbital region (Group A) and PRP injection in the left infraorbital region (Group B). They received three treatment sessions at 2-week interval, and followed up monthly for 3 months. They were evaluated clinically and dermoscopically before treatment and at the end of follow-up period. Both groups showed significant clinical improvements proved by significant reduction of degree of hyperpigmentation and tear trough rating scale. Obviously, more significant clinical and dermoscopic improvements were observed in Group A than Group B. Therefore, it could be concluded that both PPP gel and PRP were clinically effective procedures for aesthetic improvement of infraorbital region. Moreover, PPP gel seems to be significantly more effective than PRP as a therapeutic modality.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Platelet‐poor plasma gel vs platelet‐rich plasma for infraorbital rejuvenation: A clinical and dermoscopic comparative study

Neinaa

Hodeib

Morquos

et al. 2020

Dermatologic Therapy

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show abstract

“…Platelet poor plasma (PPP) gel has been used as a dermal filler for the correction of facial wrinkles, tear trough deformity and recently for the boxlike scars of chickenpox. [ 1 ]…”

Section: Surgical Challengementioning

confidence: 99%

A Novel Cost-effective Autologous Dermal Filler for Atrophic Acne Scar

Pol

Kumar

Deora

2021

Indian Dermatology Online Journal

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“…Recently plasma‐coated polycaprolactone nanofibers with covalently bonded PRP have been experimented with to prolong the effect of these biomolecules 52 . Addition of PRP to fat grafting and as a biofiller have also shown promising results 53,54 …”

Section: Applications In Dermatologymentioning

confidence: 99%

Platelet‐rich plasma—Where do we stand today? A critical narrative review and analysis

Arora

2020

Dermatologic Therapy

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“Sometimes you have to travel a long way to find what is near.” This quote by Paulo Coelho stands true for platelet‐rich plasma (PRP) as we know of it today. Large strides have been made to understand this “youth” in blood, but there still seems a long way to go in our understanding of it. Despite advances, clarity in its preparation, biology, and the properties of the final product still remains elusive. The concepts of an ideal number or concentration of platelets in the final enriched plasma, best devices to prepare PRP, an ideal hardware, standard parameters for its preparation, the need for its activation or buffering of the final preparation or whether anticoagulants should be used or not, have evolved, since it was first described. The authors present an analysis of PRP present day status and its usefulness in field of medicine with a review of published literature from “Medline” (via “PubMed”), “Cochrane,” the Virtual Health Library, and Google Scholar related to PRP, its biology, types, and classifications, preparation, and use.

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Platelet-poor plasma-based biofiller: An innovative alternative to expensive hyaluronic acid–based fillers for treatment of chicken pox scars

Cited by 9 publications

References 2 publications

Platelet‐poor plasma gel vs platelet‐rich plasma for infraorbital rejuvenation: A clinical and dermoscopic comparative study

Platelet‐poor plasma gel vs platelet‐rich plasma for infraorbital rejuvenation: A clinical and dermoscopic comparative study

A Novel Cost-effective Autologous Dermal Filler for Atrophic Acne Scar

Platelet‐rich plasma—Where do we stand today? A critical narrative review and analysis

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