Satellites have many high-, medium-, and low-frequency micro vibration sources that lead to the optical axis jitter of the optical load and subsequently degrade the remote sensing image quality. To address this problem, this paper developed an image motion detection and restoration method based on an inertial reference laser, and describe edits principle and key components. To verify the feasibility and performance of this method, this paper also built an image motion measurement and restoration system based on an inertial reference laser, which comprised a camera (including the inertial reference laser unit and a Hartmann wavefront sensor), an integrating sphere, a simulated image target, a parallel light pope, a vibration isolation platform, a vibration generator, and a 6 degrees of freedom platform. The image restoration principle was also described. The background noise in the experiment environment was measured, and an image motion measurement accuracy experiment was performed. Verification experiments of image restoration were also conducted under various working conditions. The experiment results showed that the error of image motion detection based on the inertial reference laser was less than 0.12 pixels (root mean square). By using image motion data to improve image quality, the modulation transfer function (MTF) of the restored image was increased to 1.61–1.88 times that of the original image MTF. The image motion data could be used as feedback to the fast steering mirror to compensate for the satellite jitter in real time and to directly obtain high-quality images.