Pleomorphic Adenoma of Breast-A Case Report and Review of Literature

Leekha, Nitin; Muralee, Madhu; Mathews, Anitha; Preethi, T. R.; Ahamed, M. Iqbal

doi:10.1007/s13193-014-0310-y

Cited by 13 publications

(9 citation statements)

References 8 publications

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“…There are no specific imaging findings of PA 11 . Although PA is often reported as a well-circumscribed lump, it may demonstrate irregular contours on breast ultrasound and can appear as a lump without microcalcifications on mammography 3 .…”

Section: Discussionmentioning

confidence: 99%

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Pleomorphic adenoma of the breast

et al. 2021

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Pleomorphic adenoma (PA) is a common tumor of the salivary gland, but rarely occurs in the breast. PA of the breast is a benign tumor that usually presents as a periareolar nodule. Core-needle biopsies may yield misdiagnosis with complex fibroadenoma, phyllodes tumor and metaplastic breast cancer due to the mixture of stromal and epithelial elements. We present a case of PA of the breast suspected after core-needle biopsy, but confirmed after surgical excision. The importance to make a correct diagnosis consists in avoid extensive unnecessary surgery, such as mastectomy, since PA can be treated with local surgical resection.

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Section: Discussionmentioning

confidence: 99%

“…PA typically occurs in females between 23 to 85 years of age 7 and is usually located in the periareolar region and in the right breast 13 . PA presents clinically as a breast nodule with an average size of 2 cm, which can be palpable and difficult to differentiate from breast cancer 11,14 .…”

Section: Discussionmentioning

confidence: 99%

Pleomorphic adenoma of the breast

et al. 2021

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“…PA of the breast occurs frequently in the retroareolar region in women (female:male ratio 10:1), ranging from 23 to 78 years . PA is a circumscribed lesion characterized by a mixture of cells featuring epithelial and myoepithelial phenotype embedded in an abundant stroma featuring myxoid, chondroid or osseous metaplasia . In the breast, PA has to be distinguished from matrix‐producing MBC, adenomyoepithelioma, duct adenoma and papilloma with cartilaginous metaplasia and from mucinous carcinoma on fine needle aspiration cytology …”

Section: Discussionmentioning

confidence: 99%

Pleomorphic adenoma‐like tumour of the breast

et al. 2015

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“…PA of the breast is a rare neoplasm that occurs usually in the retro‐areolar region. It presents as a circumscribed lesion characterized by a mixture of cells featuring epithelial and myoepithelial phenotypes embedded in an abundant stroma with myxoid, chondroid or osseous metaplasia . In the breast, PA has to be distinguished from matrix‐producing metaplastic carcinoma, adenomyoepithelioma and papilloma with cartilaginous metaplasia …”

Section: Breast Lesions Of Uncertain Malignant Naturementioning

confidence: 99%

Breast lesions of uncertain malignant nature and limited metastatic potential: proposals to improve their recognition and clinical management

et al. 2015

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Breast lesions comprise a family of heterogeneous entities with variable patterns of presentation, morphology and clinical behaviour. The majority of breast lesions are traditionally classified into benign and malignant conditions and their behaviour can, in the vast majority of cases, be predicted with a reasonable degree of accuracy. However, there remain lesions which show borderline features and lie in a grey-zone between benign and malignant as their behaviour cannot be predicted reliably. Defined pathological categorisation of such lesions is challenging and for some entities is recognised to be subjective and include a range of diagnoses, and forms of terminology, which may trigger over-treatment or under-treatment. The rarity of these lesions makes acquisition of clinical evidence problematic and limits the development of a sufficient evidence base to support informed decision making by clinicians and patients. Emerging molecular evidence is providing a greater understanding of the biology of these lesions, but this may or may not be reflected in their clinical behaviour. Herein we discuss some breast lesions that are associated with uncertainty regarding classification, behaviour and hence management. These include biologically invasive malignant lesions associated with uncertain metastatic potential such as low-grade adenosquamous carcinoma, low-grade fibromatosis-like spindle cell carcinoma and encapsulated papillary carcinoma. Other lesions remain of uncertain malignant nature such as mammary cylindroma, atypical microglandular adenosis, mammary pleomorphic adenoma and infiltrating epitheliosis. The concept of categories of 1) breast lesions of uncertain malignant nature and 2) breast lesions of limited metastatic potential, are proposed with details of which histological entities could be included in each category, and their management implications are discussed.

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Pleomorphic Adenoma of Breast-A Case Report and Review of Literature

Cited by 13 publications

References 8 publications

Pleomorphic adenoma of the breast

Pleomorphic adenoma of the breast

Pleomorphic adenoma‐like tumour of the breast

Breast lesions of uncertain malignant nature and limited metastatic potential: proposals to improve their recognition and clinical management

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