PLGA/β-TCP composite scaffold incorporating cucurbitacin B promotes bone regeneration by inducing angiogenesis

Cheng, Wenxiang; Liu, Yanzhi; Meng, Xiangbo; Zheng, Zheng-Tan; Li, Lingli; Ke, Liqing; Li, Ling; Huang, Cuishan; Zhu, Guo‐Yuan; Pan, Hudan; Qin, Ling; Wang, Xinluan; Zhang, Peng

doi:10.1016/j.jot.2021.10.002

Cited by 33 publications

(30 citation statements)

References 47 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…combined magnesium particles with bone cement to further enhance bone repair by promoting angiogenesis [ 36 ]. The study by Cheng and Liu also illustrates the importance of angiogenesis for bone repair [ 37 , 38 ]. Xie et al.…”

Section: Discussionmentioning

confidence: 99%

Mediation of mechanically adapted TiCu/TiCuN/CFR-PEEK implants in vascular regeneration to promote bone repair in vitro and in vivo

Chen

Zhang

et al. 2022

Journal of Orthopaedic Translation

View full text Add to dashboard Cite

Section: Discussionmentioning

confidence: 99%

Mediation of mechanically adapted TiCu/TiCuN/CFR-PEEK implants in vascular regeneration to promote bone repair in vitro and in vivo

Chen

Zhang

et al. 2022

Journal of Orthopaedic Translation

View full text Add to dashboard Cite

“…Initially, exogenous scaffolds were only employed to simulate the spatial structure of the ECM, and included tricalcium phosphate (TCP) [ 70 ], polylactic acid, polycaprolactone (PCL), and chitosan [ 66 ] ( Fig. 4 ).…”

Section: Composition and Application Of Tissue-engineered Periosteummentioning

confidence: 99%

Periosteum and development of the tissue-engineered periosteum for guided bone regeneration

Zhang

Wang

Yang

et al. 2022

Journal of Orthopaedic Translation

View full text Add to dashboard Cite

“…Bone repair is a complex process involving complex linkages between osteoblasts, the ECM, and bone-inducing factors and is affected by bacterial toxin-based oxidative stress [81]. Natural-based hydrogels can mimic the ECM [214] by introducing bone-inducing materials to accelerate bone repair and angiogenesis [88,89,207,212,[215][216][217][218][219][220][221][222][223][224][225]. However, in some specific bone defect sites, the current natural hydrogels cannot meet the clinical requirements for fast bonding and high mechanical strength.…”

Section: Bone Tissue Repairmentioning

confidence: 99%

Natural polymer‐based adhesive hydrogel for biomedical applications

Long

Xie

2022

Biosurface and Biotribology

View full text Add to dashboard Cite

Hydrogel is a polymer network system that can form a hydrophilic three‐dimensional network structure through different cross‐linking methods. In recent years, hydrogels have received considerable attention due to their good biocompatibility and biodegradability by introducing different cross‐linking mechanisms and functional components. Compared with synthetic hydrogels, natural polymer‐based hydrogels have low biotoxicity, high cell affinity, and great potential for biomedical fields; however, their mechanical properties and tissue adhesion capabilities have been unable to meet clinical requirements. In recent years, many efforts have been made to solve these issues. In this review, the recent progress in the field of natural polymer‐based adhesive hydrogels is highlighted. The authors first introduce the general design principles for the natural polymer‐based adhesive hydrogels being used as excellent tissue adhesives and the challenges associated with their design. Next, their usages in biomedical applications are summarised, such as wound healing, haemostasis, nerve repair, bone tissue repair, cartilage tissue repair, electronic devices, and other tissue repairs. Finally, the potential challenges of natural polymer‐based adhesive hydrogels are presented.

show abstract

PLGA/β-TCP composite scaffold incorporating cucurbitacin B promotes bone regeneration by inducing angiogenesis

Cited by 33 publications

References 47 publications

Mediation of mechanically adapted TiCu/TiCuN/CFR-PEEK implants in vascular regeneration to promote bone repair in vitro and in vivo

Mediation of mechanically adapted TiCu/TiCuN/CFR-PEEK implants in vascular regeneration to promote bone repair in vitro and in vivo

Periosteum and development of the tissue-engineered periosteum for guided bone regeneration

Natural polymer‐based adhesive hydrogel for biomedical applications

Contact Info

Product

Resources

About